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題名 | Fiber-optics based Optical Coherence Tomography for Biomedical Application=生醫應用之光纖式光學同調斷層掃描 |
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作者 | 廖坤鴻; 羅增成; 楊志忠; 林啟萬; Liao, Kun-hung; Luo, Tzeng-cherng; Yang, Chih-chung; Lin, Chii-wann; |
期刊 | Journal of Medical and Biological Engineering |
出版日期 | 20030300 |
卷期 | 23:1 2003.03[民92.03] |
頁次 | 頁7-12 |
分類號 | 416.14 |
語文 | eng |
關鍵詞 | 光學同調斷層掃描; 光學相位延遲器; 手持式造影探頭; 影像失真補償; Optical coherence tomography; Optical phase delay line; Handheld probe; Imaging distortion compensation; |
中文摘要 | 光學同調斷層掃描,為近年來快速進步的非侵入式醫學造影系統,其基本原理為使用低同調之光源,照射於生物組織,並以反射式干涉術量測背向散射光,可藉由不同機制之掃描方式,重建出二維或三維之生物組織影像,並具有達微米級之高空間解析度。我們完成一套光纖式光學同調斷層掃描系統,為了增加系統之臨床實用性,故以光學相位延遲器做為參考端之快速掃描,配合手持式造影探頭為樣本端之掃描,亦針對掃描深度之強度失真問題,進行最佳化補償,以增進影像之品質。 |
英文摘要 | Optical coherence tomography (OCT) is a fast evolving noninvasive imaging technology for biomedicine in recent years. Its fundamental principle is to use a low coherent light on biological sample and collect the backscattering light with an interferemeter configuration. It can achieve high spatial resolution of several micrometers and reconstruct two or three-dimensional images with various scanning mechanisms. Based on a fiber-optics based OCT, we implemented an optical delay-line on the reference arm for fast scanning speed and a handheld probe on sampling arm for surface scanning applications. We also reported a simple image compensation scheme, which is based on the distortion profile of scan depth, to enhance the image quality. |
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