頁籤選單縮合
題名 | Antitumor Agents. 2. Synthesis and Cytotoxic Evaluation of 10-Bromorutaecarpine= |
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作者 | 楊禮明; 林淑娟; 林麗純; 郭曜豪; Yang, Li-ming; Lin, Shwu-jiuan; Lin, Lie-chwen; Kuo, Yao-haur; |
期刊 | 中華藥學雜誌 |
出版日期 | 19990600 |
卷期 | 51:3 1999.06[民88.06] |
頁次 | 頁219-225 |
分類號 | 414.33 |
語文 | eng |
關鍵詞 | Evodia rutaecarpa; Quinazolinocarboline alkaloid; Antitumor; Rutaecarpine; |
英文摘要 | Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF-295 and ovarian cancer cell lines. |
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