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相關文獻
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頁籤選單縮合
題名 | Maxillary Growth after Palatal Denudation: An Animal Experiment=侸骨裸露對顏面生長的影響:動物實驗 |
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作者 | 張家寧; 羅綸洲; 洪凱風; 陳國鼎; 陳昱瑞; 羅慧夫; | 書刊名 | 長庚醫學 |
卷期 | 22:3 1999.09[民88.09] |
頁次 | 頁378-385 |
分類號 | 416.413 |
關鍵詞 | 侸裂; 侸裂手術; 顎骨生長限制; Cleft palate; Palate surgery; Maxillary growth restriction; |
語文 | 英文(English) |
中文摘要 | 背景:一般認為早期的 裂手術可能會導致上顎的生長限制,在手術時骨骼的暴 露隨後會有疤痕的形成在表面上,此可能為限制生長的原因,這項研究我們以動物實驗來評 估這個問題。 方法:實驗首先將4星期大的白鼠分成3組,第一組於其硬 兩側臼齒旁之骨膜黏膜做 條狀切除,第二組的小白鼠則接受在硬 兩側骨膜黏膜做皮瓣提起並重新覆蓋之手術,第三 組則為沒有做任何手術之對照組。手術均於手術顯微鏡下進行,以使組織做更細微之處理, 並避免傷及底下的骨頭。這些動物於平均11週後宰殺並將頭骨加以處理以做進一步測量, 測量內容包括上 骨大臼齒間的寬度,上 之垂直高度及長度。 結果:統計結果顯示,實驗組之 骨寬度及 的長度有顯著減少,然上顎之垂直高度則 並無差異。 討論:此研究可確認開刀所造成之 骨骨頭暴露會導致上顎骨生長異常。 |
英文摘要 | Background: Palate surgery at an early age may cause retardation of maxillary growth. The second intention healing of the raw bone surface created on the palate is considered to be the cause of the growth retardation. The animal experiment in this study was designed to evaluate this effect. Methods: Four-week-old Sprague-Dawley rats were divided into 3 groups. In the first group, a strip of mucoperiosteum was excised on both sides of the hard palate. A second group of rats received a sham surgery in which bilateral mucoperiosteal flaps were raised and redraped. The third group served as controls with no surgery. Flap elevation with and without excision was performed under an operative microscope to facilitate the delicate manipulation of tissue and to avoid injury to the underlying bone. The animals were killed 11 weeks later and the skulls were prepared for measurements, which included the palatal inter-molar width, maxillary height, and maxillary length. Results: The results revealed statistically significant decreases in palatal width and maxillary length in the experimental group (excision of mucoperiosteum). No differences were observed in the vertical height of the maxilla. Conclusion: This study confirms that surgically created bone denudation of the palate causes maxillary growth disturbances. |
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