查詢結果分析
相關文獻
- Effects of Prokinetic Agents on Contractile Responses to Electrical Field Stimulation of Isolated Guinea Pig Trachea
- 冷飲冰水對天竺鼠氣管收縮的影響
- The Nonadrenergic Noncholinergic System Can Modulate the Effect of Prokinetic Agents on Contractile Response of Isolated Guinea-Pig Trachea Segments to Electrical Field Stimulation
- 比較三十種常用於治療咳嗽的中藥對天竺鼠氣管經藥物誘導收縮後的鬆弛影響
- 劑量化電刺激訓練對膝伸肌等速肌力之影響系列研究(2)
- Influence of Morning or Evening Administration on Absorption of Theophylline
- 柴朴湯對卵蛋白過敏原誘發天竺鼠氣喘之影響
- 急迫性尿失禁之物理治療
- Effects of Alkylidenephthalides on the Pituitrininduced Alternations in Isolated Guinea Pig Hearts
- The Electrophysiological and Mechanical Effects of Atrial Natriuretic Peptide and Acetylcholine on Guinea Pig Ventricular Papillary Muscle
頁籤選單縮合
題 名 | Effects of Prokinetic Agents on Contractile Responses to Electrical Field Stimulation of Isolated Guinea Pig Trachea=促進腸蠕動藥物對天竺鼠氣管電刺激收縮反應之影響 |
---|---|
作 者 | 鄒國英; 柯逢年; 簡志澔; | 書刊名 | 臺灣醫學會雜誌 |
卷 期 | 98:8 1999.08[民88.08] |
頁 次 | 頁567-572 |
分類號 | 418.24 |
關鍵詞 | 促進腸蠕動藥物; 天竺鼠; 氣管; 電刺激; 收縮; Trachea; Guinea pig; Metoclopramide; Cisapride; Prokinetic agent; Electrical field stimulation; |
語 文 | 英文(English) |
英文摘要 | We investigated the effects of two prokinetic agents, metoclopramide and cisapride, on the contractile response of isolated guinea pig tracheal segments exposed to electrical field stimulation (EFS). Tracheal segments were suspended between two platinum electrodes in organ baths. Frequency-response curves were obtained by increasing the frequency of the stimuli on equilibrated tracheal segments, in a stepwise manner. Metoclopramide potentialed the EFS-induced contraction of the tracheal; the potentiation was more prominent at lower stimulation frequencies (≧ 10 Hz). Cisapride significantly inhibited the electrically stimulated contraction in trachea strips when the frequency of the stimulus was higher than 10 Hz. In the presence of both metoclopramide and cisapride, there was a potentiation of the contractile response at lower frequencies, and this potentiation was reduced when the frequency was higher than 10 Hz. These results demonstrate that metoclopramide enhances and cisapride reduces the airwaytonicity elicited by EFS in isolated guinea pig trachea segments. Further studies are needed to verify the effects of these prokinetic agents on EFS-induced contraction of isolated guinea pig trachea and to determine the mechanisms involved. |
本系統中英文摘要資訊取自各篇刊載內容。