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頁籤選單縮合
題名 | Hydrops Fetalis with Complete Heart Block Secondary to Congenital Lupus: Report of One Case=先天性狼瘡及完全房室阻斷合併胎兒水腫:一病例報告 |
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作者 | 洪嘉琳; 林姃慧; 穆淑琪; 宋增銓; | 書刊名 | 臺灣兒科醫學會雜誌 |
卷期 | 40:4 民88.07-08 |
頁次 | 頁265-267+292 |
分類號 | 417.517 |
關鍵詞 | 新生兒狼瘡; 完全房室阻斷; 胎兒水腫; Neonatal lupus erythematosus; Complete heart block; Hydrops fetalis; |
語文 | 英文(English) |
中文摘要 | 先天性狼瘡並非為一常見疾病。其臨床表現常為永久性的先天完全性房室阻斷或 皮疹或兩者合併出現。我們報告一男嬰併有先天性狼瘡,母親患有全身性紅斑狼瘡。此男嬰 臨床表現上不但有皮疹,完全房室阻斷而且合併胎兒水腫。經胎盤傳遞的母親抗體包括 Anti-SSA/Ro及Anti-SSB/La皆呈陽性反應。雖然產前有給與母親抗心衰竭藥物及類固醇治 療,出生後給與放置心房調節器及強心藥物使用,此男嬰仍然在出生後第二天死亡。先天性 狼瘡及房室阻斷合併胎兒水腫很罕見且預後常是致命的。 |
英文摘要 | Neonatal lupus erythematosus is an uncommon syndrome characterized by a congenital heart block and/or cutaneous lesion. We report a male newborn with neonatal lupus erythematosus presenting with complete heart block, cutaneous lesions, and hydrops. Transplacental passage of anti-SSA/Ro and anti-SSB/La antibodies were positive. Under the regimens of steroid for maternal systemic lupus erythematosus, perinatal anticongestive agents, and postnatal ventricular pacing with inotropic therapy, the infant died at the age of two days. The prognosis of hydrops fetalis secondary to neonatal lupus with complete heart block is usually fatal. |
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