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題名 | Transcranial Doppler Monitoring with Head-Upright Tilting in Patients with Syncope=暈厥病人之腦血流動力研究:穿顱超音波及傾斜床之應用 |
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作者 | 許立奇; 陳昌明; 盛文鴦; 翁文章; 陸仁安; 胡漢華; | 書刊名 | 中華醫學雜誌 |
卷期 | 62:8 1999.08[民88.08] |
頁次 | 頁544-549 |
分類號 | 415.81 |
關鍵詞 | 腦血流動力學; 傾斜床; 暈厥; 穿顱超音波; Cerebral hemodynamics; Head-upright tilt; Syncope; Transcranial doppler ultrasonography; |
語文 | 英文(English) |
英文摘要 | BACKGROUND: The aim of our study was to evaluate the effects of orthostatic stress produced by the head-upright tilt test on human cerebral hemodynamics by transcranial Doppler sonography. METHODS: We studied 60 subjects who were divided into two groups; one of normal controls (n = 43) and one of patients suffering from syncope (n = 17). A 30- minute head-upright tilt test was conducted on all subjects, and heart rate and blood pressure were monitored by surface electrocardiography and cuff sphygmomanometry, respectively. Cerebral blood flow velocity and cerebral vasoreactivity were continuously monitored using transcranial Doppler sonography. RESULTS: The maximal decreases in mean blood pressure of controls and patients with syncope were 2.6 +/- 7.8% and 0.5 +/- 7.9% of baseline, respectively. The maximal decreases in mean blood flow velocity in the middle cerebral artery between the two groups reached 19.6 +/- 6.2% and 30.7 +/- 14.1% of baseline, respectively (p < 0.05). The increases in pulsatility index between the two groups were 15.4 +/- 14.3% and 16.9 +/- 21.1% of baseline, respectively. CONCLUSION: The responses of cerebral blood flow to upright tilting differed significantly between normal controls and patients with syncope, implying that the latter may suffer an impairment of cerebral autoregulation. Further studies are needed to ascertain what clinical implications this finding might have. |
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