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題名 | Glucagonoma Syndrome: A Case Report=升糖素瘤症候群:一病例報告 |
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作者 | 石宜銘; 蘇正熙; 李建賢; 吳秋文; 雷永耀; Shyr, Yi-ming; Su, Cheng-hsi; Lee, Chen-hsen; Wu, Chew-wun; Lui, Wing-yiu; |
期刊 | 中華醫學雜誌 |
出版日期 | 19990900 |
卷期 | 62:9 1999.09[民88.09] |
頁次 | 頁639-643 |
分類號 | 416.248 |
語文 | eng |
關鍵詞 | 糖尿病; 升糖素瘤; 高升糖素血症; 潰爛性移行性紅斑; 胰腫瘤; Diabetes mellitus; Glucagonoma; Hyperglucagonemia; Necrolytic migratory erythema; Pancreatic tumor; |
英文摘要 | Glucagonoma is a very rare islet cell tumor of the pancreas. We present a case of pancreatic tail tumor with the typical glucagonoma syndrome of necrolytic migratory erythema (NME), diabetes mellitus (DM), anemia, weight loss and glossitis. After complete resection of the pancreatic tumor, the glucagonoma syndrome subsided. In reviewing 120 cases of glucagonoma in the literature, the average tumor diameter was 3.6 cm. Most (68.1%) of the tumors occurred in the pancreatic tail. Two-thirds of the reported glucagonomas were malignant and 53.5% metastasized to other organs. The curative resection rate was 45.8%. A triad of pancreatic tumor, NME and DM should lead to the diagnosis of glucagonoma. |
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