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題名 | 原田氏病之神經耳科學所見=Neurotological Findings in Harada Disease |
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作者 | 陳修宜; 楊怡和; 林昌平; | 書刊名 | 臺灣醫學 |
卷期 | 3:4 1999.07[民88.07] |
頁次 | 頁383-387 |
分類號 | 416.81 |
關鍵詞 | 原田氏病; 眩暈; 重聽; Harada disease; Vertigo; Hearing loss; |
語文 | 中文(Chinese) |
中文摘要 | 原田氏病是一種罕見的自體免疫性疾病,病患會產生抗體侵犯全身含黑素細胞的 組織,包括眼睛、內耳、皮膚、毛髮及腦膜等,而表現出各種症狀,諸如視力喪失、內耳症 狀 (眩暈、耳鳴、重聽 )、白斑、禿髮、毛髮變白及頭痛。 自 1994 年 4 月至 1998 年 3 月,計四年間, 經本院眼科診斷為原田氏病者共 43 名; 其中 19 名 (44%) 仲有內耳症狀 ,包括重聽、耳鳴、或眩暈。患者接受詳細的病史詢問、耳鼻喉局部鏡檢、及一系列的聽力 平衡功能檢查。 結果 19 名具內耳症狀的原田氏病患者,計男性 10 名、女性 9 名,年齡 分佈在 16 至 72 歲之間, 平均為 41 歲。 在臨床症狀方面,視力模糊 19 例,聽力喪失 12 例、頭痛 11 例、眩暈或頭暈 10 例,而耳鳴 5 例。 在聽力圖型的分佈,14 耳正常、 18 耳呈高音漸傾型、4 耳呈水平型,其他型則有 2 耳。經給予高劑量類固醇治療後,重聽 及眩暈的情況均獲改善。臨床上,當耳鼻喉科醫師面對同時仲有紅眼睛及內耳症狀的病人前 來求診時,需考慮原田氏病的可能性,進而照會眼科醫師以確立診斷。 |
英文摘要 | Background: Harada disease, or Vogt-Koyanagi-Harada syndrome, is a rare autoimmune disease characterized by autoantibodies that attack melanocyte-containing tissues or organs such as skin, hair, meninges, uvea, and the inner ear. The clinical manifestations include neurological symptoms (headache and meningismus), dermatological symptoms (alopecia, vitiligo, and poliocytosis), ophthalmological symptoms (vision loss), and inner ear symptoms (vertigo, tinnitus, and hearing loss). A total of 43 patients with Harada disease were treated at our hospital from April 1994 through March 1998. Nineteen of these patients had inner ear symptoms and were referred to the otolaryngological department for further evaluation, suits: The patients comprised 10 men and 9 women, ranging in age from 16 to 72 years. Clinically, all developed blurred vision, 12 had hearing loss, 11 had headache, and 5 had tinnitus. Audiogram types included sloping type (18 ears), normal hearing (14 ears), flat type (4 ears), and others (2 ears). High-dose steroid treatment greatly improved vertigo in 4 patients. Harada disease should be taken into consideration in the differential diagnosis in patients with red eyes and inner ear symptoms. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。