頁籤選單縮合
題名 | Successfully Treated Central Nervous System Burkitt's Lymphoma with Minimal Extraneural Disease in a Child=孩童中樞神經系Burkitt氏淋巴瘤併微小神經系外病灶治療成功病例 |
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作者 | 楊兆平; 萬永亮; 洪悠紀; | 書刊名 | 臺灣醫學會雜誌 |
卷期 | 98:1 1999.01[民88.01] |
頁次 | 頁66-69 |
分類號 | 417.554 |
關鍵詞 | 中樞神經系Burkitt氏淋巴瘤併微小神經系外病灶治療; Burkitt's lymphoma; Central nervous system lymphoma; Chemotherapy; Imaging studies; |
語文 | 英文(English) |
英文摘要 | Burkitt's lymphoma, the most common childhood non-Hodgkin's lymphoma, usually presents with abdominal tumors, Central nervous system (CNS) involvement in Burkitt's lymphoma is mostly secondary to advanced systemic disease, rarely with brain parenchymal lesions, and was previously recalcitrant to treatment. We report an unusual case of CNS Burkitt's lymphoma with minimal extraneural disease, This 10-year-old immunocompetent boy presented with increased intracranial pressure and seizures and was found to have multifocal intracerebral lesions on brain imaging studies. Cerebrospinal fluid studies confirmed the presence of Burkitt's lymphoma cells. Abdominal computed tomography showed bilateral nephromegaly with left intrarenal lesions that disappeared after three doses of intravenous dexamethasone. The patient was treated for 6.5 months according to the LMB 89 group C protocol of the French Pediatric Oncology Society. The response was brisk and complete. The patient has been disease free for more than 4 years, and is believed to be cured, |
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