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頁籤選單縮合
題名 | KIKUCHI氏病--病例報告=Kikuchi's Disease: A Case Report |
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作者 | 陳永煌; 劉博仁; 袁本治; | 書刊名 | 醫學研究 |
卷期 | 19:1 1998.07[民87.07] |
頁次 | 頁61-64 |
分類號 | 415.6 |
關鍵詞 | Kikuchi氏病; 淋巴腺炎; Kikuchi's disease; Lymphadenitis; |
語文 | 中文(Chinese) |
中文摘要 | Kikuchi氏病(Kikuchi's disease)或組織細胞壞死性淋巴腺炎(histiocytic necrotizing lymphadenitis)是一良性、自限性的淋巴腺炎,其好發於東方的年輕女性,臨床症狀常有頸部淋巴腺腫、發燒、疲倦等。實驗室檢查可見顆粒球變少(granulocytopenia)和淋巴球增生(lymphocytosis)。在診斷上最主要的依據為淋巴腺的病理切片檢查及臨床表現。而其致病原因至今仍不明,可能的原因為病毒感染或免疫過度反應。本院於民國86年8月及10月發現兩個病例,其因頸部淋巴腺腫、發燒、疲倦、皮膚紅疹有數日之久而至本院門診,經住院檢查,排除惡性腫瘤的可能後,施行淋巴腺切除手術,術後病理報告為Kikuchi氏病。經查閱文獻,因屬罕見,故提出本文,並回顧文獻,就疾病的病理特性、臨床症狀、好發之年齡、性別、治療、預後等,提出報告與討論。 |
英文摘要 | Kikuchi's disease or histiocytic necrotizing lymphadenitis (HNL) is a benign disease, predominantly of young women under 30 years old. It was a self-limiting disease of unknown origin that causes cervical lymphadenitis. The disease was first detected in Japan by Kikuchi in 1972. Symptoms of HNL include tender cervical adenopathy, fever, body weight loss and night sweating. Laboratory studies reveal leukopenia with relative granulocytopenia and lymphocytosis. The diagnosis is based on histopathological findings in open biopsy. It reveals areas with frank cellular necrosis, karyorrhexis, and absence of plasma cells. Differential diagnosis with malignant lymphoma is difficult both clinically and histopathologically. We present two cases of Kikuchi's disease for detail discussion about the diagnosis and treatment. |
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