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題名 | Evidence of Epstein-Barr Virus in Lymphoepithelioma-like Carcinoma of the Uterine Cervix: A Case Report=EBV存在於子宮頸類淋巴上皮癌的證據:一例報告 |
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作者 | 曾令鴻; 曾志仁; 宋永魁; 薛綏; 包家駒; Tseng, Ling-hong; Tseng, Chih-jen; Soong, Yung-kuei; Hsueh, Swei; Pao, Chia C; |
期刊 | 長庚醫學 |
出版日期 | 19980600 |
卷期 | 21:2 1998.06[民87.06] |
頁次 | 頁184-188 |
分類號 | 417.2832 |
語文 | eng |
關鍵詞 | 子宮頸癌; 子宮頸類淋巴上皮細胞癌; EB病毒; 聚合酶連鎖反應; Cervical cancer; Lymphoepithelioma-like carcinoma; Epstein-Barr virus; EBV; Polymerase chain reaction; PCR; |
中文摘要 | 子宮頸類淋巴上皮細胞癌(LELLC)是十分罕見的;其臨床上的特徵少有血路及 淋巴轉移,劇烈之細胞炎症反應,且預後較好。LELC發生的機轉,就如同子宮頸癌一般仍 有許多爭論;EBV在鼻咽癌的致病機轉上佔著很重要的角色。LELC其病理特徵和鼻咽癌 十分類似,故有人認為也許EBV在LELC的發生上也扮演同樣角色,以往的文獻都無法證 明這一點;我們用聚合脢連鎖反應(PCR)的方法在LELC的細胞內發現了EBV的存在, 故本文乃報告首例LELC和EBV有關的文章,也希望啟開LELC更多了解。 |
英文摘要 | Lymphoepithelioma-like carcinoma of the uterine cervix is very rare. A 71-year-old woman, who had cervical cancer stage IB, presented lymphoepithelioma-like carcinoma pathologically. The neoplasm revealed an undifferentiated, nonkeratinizing carcinoma, which contained prominent vesicular nucleoli histologically. Epstein-Bar virus (EBV) DNA and HPV-16 DNA were demonstrated in cancer cells when using polymerase chain reaction. The patient underwent a radical hysterectomy with bilateral pelvic lymph node dissection and bilateral salpingooophorectomy. Her postoperative course was uneventful. The literature and pathologic findings are reviewed and discussed. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。