頁籤選單縮合
題名 | Vibrio vulnificus Infections: Experience of Thirteen Cases in Southern Taiwan=創傷弧菌感染:南臺灣十三名病例的經驗 |
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作者 | 蔡文正; 劉永慶; 顏慕庸; 王任賢; 陳垚生; 王堯顯; 萬樹人; 林鍚勳; | 書刊名 | 微免與感染雜誌 |
卷期 | 31:1 1998.03[民87.03] |
頁次 | 頁46-50 |
分類號 | 414.83 |
關鍵詞 | 創傷弧菌感染; Vibrio vulnificus; Bacteremia; Wound infection; |
語文 | 英文(English) |
中文摘要 | 在高雄榮民總醫院四年內共有十三位病人發生海洋創傷弧菌的感染,這些細菌都 是從血液中或無菌組織中所培養出來。病人的年齡範圍從40至86歲(平均63歲),男與女的 比例是10:3,除一位病人無皮膚病灶外,其他十二位病人都有。七位有菌血症的病人當中有 五位死亡,且大部份發生在住院24小時內。六位只有傷口感染而無菌血症的病人均存活。十 三位病人中有十一位病人有潛在性疾病。所有的病人均接受抗生素的治療且有七位病人接受 外科處理,包括切開引流、筋膜切開術、清創術、或截肢。十三位病人中有十一位病人有危 險因子,六位被甲殼類動物如蝦、蟹等剌傷,三位皮膚有傷口接觸海水,二位有生食海鮮。海 洋創傷弧菌在抗生素敏感性試驗中對很多抗生素敏感,包括tetracycline, ceftazidime, cefotaxime, gentamicin, imipenem, chloramphenicol, minocycline, amikacin。在這十 三位病人中,大部份存活的病人是接受ceftazidime加上minocycline或tetracycline治療 以及早期外科處理。這十三位病人中,原發性菌血症的死亡率是75%,傷口感染的死亡率是 23%。 |
英文摘要 | During the period of August 1991 to September 1995, Vibrio vulnificus was isolated from blood or normally sterile tissues in 13 patients at the Veterans General Hospital-Kaohsiung. Their ages ranged from 40 to 86 years (mean:63 years), and the male-to-female ratio was 10:3. All the patients except one presented with wound infection. Seven patients presented with bacteremia, 5 died mostly, within 24 hours of hospitalization. Six patients had wound infections without bacteremia and all survived. Eleven of the 13 patients had underlying diseases. All the patients received antibiotic treatment and 7 patients received surgical intervention, including incision and drainage, fasciotomy, debridement or amputation. Eleven patients had overt precipitating factors, 6 were pricked by shellfish, 3 were exposed to seawater, and 2 ate raw seafood. V. vulnificus is susceptible to a wide variety of antibiotics in vitro (tetracycline, ceftazidime, cefotaxime, gentamicin, imipenem, chloramphenicol. minocycline, amikacin) according to tests using the agar dilution technique. In our study, patients who survived received ceftazidime plus either minocycline or tetracycline, and early surgical intervention. The case fatality rates in primary bacteremia and wound infection were 75% and 23%, respectively, in our series. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。