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題 名 | 豬丹毒多價不活化菌苗之田間應用試驗--添加抗菌物質飼料對豬丹毒菌苗免疫效果影響評估試驗=Field Trlals of Poly-Valent Bacterins for Erysipelas Control--Evaluation of Immunity Effects on Pigs Vaccinated with Erysipelas Vaccines with Feed Containing Antimicrobial Additives |
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作 者 | 呂清泉; 陳清; 賴俊雄; 柯浩然; 郭乃維; 詹益波; 葉啟明; 張文章; 蕭宏孟; 陳茂振; 邱蘭皓; 羅壬松; | 書刊名 | 臺灣省家畜衛生試驗所研究報告 |
卷 期 | 33 1997[民86.] |
頁 次 | 頁47-57 |
分類號 | 437.657 |
關鍵詞 | 豬丹毒; 弱毒活菌苗; 不活化菌苗; 抗菌物質添加劑; 發育凝集抗體價; Erysipelas; Attenuated vaccine; Inactivated vaccine; Antimicrobial additives; Growth agglutination titer; |
語 文 | 中文(Chinese) |
中文摘要 | 豬丹毒弱毒活菌苗免疫豬群,於其每噸飼料中添加 1.2 公斤之 SP-500 添加劑飼 養組,菌苗免疫後第 3、6 及 12 週分別採血,測試其血清抗豬丹毒強毒株(臺灣分離;1a )發育凝集抗體價( Growth agglutination titer, G.A titer ), 其幾何平均值( Geometric mean titer, GMT )分別為 1:16, 1:14.9 及 1:19.7 與同飼養組豬丹毒不 活化菌苗免疫豬群,血清中抗體價分別為 1:7,1:9.2 及 1:7 相較,具明顯差異。顯示 弱毒活菌苗免疫豬群在本飼養組狀態下,其免疫效果似不受該抗菌劑添加之影響。另外,每 噸飼料中添加 0.3 公斤 Amoxicillin 及 1.0 公斤 Chloramphenicol 添加劑飼養組免疫豬 群,弱毒菌苗免疫後 3、6 及 12 週, 其 G.A titer 分別為 1:9.8,1:7.5 及 1:7 與 同飼養組不活化菌苗色疫豬群血清中抗體價分別為 1:7,1:9.2 及 1:8 相較並無多大差 異,但與添加 SP-500 飼養組相較,顯示本飼養組弱毒活菌苗之免疫效果受到抑制作用。而 兩組不活化菌苗所產生之發育凝集抗體價略為相同。 由攻擊試驗結果得知,不活化菌苗免疫豬群,各組之發育凝集抗體價雖偏低,但並無因添加 抗菌劑之不同而有明顯差異,免疫豬群經強毒攻擊後,除一頭斃死外,其餘雖有不同程度之 攻擊反應,但大部份豬隻仍如同弱毒活菌苗免疫豬群能耐過活存。 |
英文摘要 | The geometric mean titer (GMT) of the growth agglutination (GA) titers of swine vaccinated with attenuated Erysipelas vaccine against la serotype strain isolated in Taiwan were round to be 1:16,1:14.9 and 1:19.7, respectively, at 3,6 and 12 weeks after vaccination in feeding condition with feed containing 1.2 kg/ton of SP-500 additive. Those GA titers were distinguishable from the counterparts measured, respectively, 1:7,1:9.2 and 1:7 from the group of pigs inoculated with inactived bacterin under the same feeding condition. It indicated that the immunity abilities of the pigs immunized with attenuated vaccine were not affected by that antimicrobial additive. On the other hand, two groups of pigs were fed with Amoxicillin 0.3kg + Chloramphenicol 1.0kg per ton additives. The GMT of the GA titers were 1:9.8,1:7.5 and 1:7 for the group of pigs immunized with attenuated vaccine. Compared to the GMT of the GA titers of 1:7,1:9.2, and 1:8 obtained from the group of pigs with inactivated bacterin vaccination under the same feed condition, the resulting GA titers were slmilar, Comparing the two groups of pigs inoculated with attenuated vaccine but fed with different additives, the immunity effects of the pigs were inhibited under the second feed condition. On the contrary, the GMT of the GA titers were at the same level under both feed conditions for the groups of pigs vaccinated with inactivated bacterin. Although the GA titers were low in all groups of pigs vaccinated with inactivated bacterin, the GMT titers were not distinctly different in the two additive groups tested. Based on the challenge exposure to virulent strain, the results indicated that all groups of pigs showed various degree of challenge reactions. In the end, except for one dead pig in the group with inactivated bacterin vaccination, the rest survived like the group of pigs vaccinated with attenuated vaccine. |
本系統中英文摘要資訊取自各篇刊載內容。