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題名 | Management of Ascites in Patients with Liver Cirrhosis: Recent Evidence and Controversies= |
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作者 | Hsu, Shao-jung; Huang, Hui-chun; |
期刊 | Journal of the Chinese Medical Association |
出版日期 | 20130300 |
卷期 | 76:3 2013.03[民102.03] |
頁次 | 頁123-130 |
分類號 | 415.534 |
語文 | eng |
關鍵詞 | Ascites; Liver cirrhosis; Portal hypertension; |
英文摘要 | Ascites formation in patients with cirrhosis, portal hypertension, or both usually results from hyperdynamic circulatory dysfunction, where the retention of sodium and water is associated with the activation of the sympathetic and renineangiotensinealdosterone systems. The presence of ascites indicates the development of liver decompensation. Furthermore, complications seen in conjunction with ascites such as spontaneous bacterial peritonitis, hepatorenal syndrome, and hepatic hydrothorax may result in increased morbidity and mortality. Although nonpharmacological, pharmacological, and surgical approaches have been introduced and clinically practiced, their therapeutic effects are still suboptimal or limited by their potential side effects, such as large-volume paracentesis-induced postparacentesis circulatory dysfunction. Herein, we discuss strategies to prevent and properly manage ascites-related complications, including a review of the literature and controlled studies that assess these strategies. |
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