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- Retinoic Acid Syndrome: A Case Report
- 急性前骨髓性白血病人使用ATRA治療後疑似引發急性心肌梗塞之個案報告
- 砒霜--三氧化二砷在急性前骨髓性白血病患者治療之角色
- Subdural Hemorrhage in a Child with Acute Promyelocytic Leukemia Presenting as Subtle Headache
- Deeper and Early Molecular Response Is a Good Predictor for Risk of Relapse in Patients with Acute Promyelocytic Leukemia
- 三氧化二砷用於急性前骨髓性白血病的治療
- Histiocytoid Sweet's Syndrome during Induction Therapy with All-trans Retinoic Acid for Acute Promyelocytic Leukemia: A Case Report
頁籤選單縮合
題名 | Retinoic Acid Syndrome: A Case Report=維生素A酸症候群:一病例報告 |
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作者 | 曹玄明; 徐會棋; | 書刊名 | 中華醫學雜誌 |
卷期 | 60:5 1997.11[民86.11] |
頁次 | 頁273-276 |
分類號 | 415.635 |
關鍵詞 | 急性前骨髓性白血病; 全反式維生素A酸; 維生素A酸症候群; Acute promyelocytic leukemia; All-trans-retinoic acid; Differentiation; Retinoic acid syndrome; |
語文 | 英文(English) |
中文摘要 | 全反式維生素A酸具有將急性前骨髓性白血病細胞誘導分化為正常顆粒性白血球藥效,近年來已被成功應用於臨床治療上。它的使用可避免傳統化學治療的許多併發症,但也在部分病人身上產生致命的副作用,我們報告的這病例即在全反式維生素A酸治療一周內發生水腫、高燒、氣促以及呼吸衰竭之狀況。但在迅速給予類因醇及化學治療後,病情隨即穩定。最後順利達到完全緩解。 |
英文摘要 | All-trans-retinoic acid (ATRA) is a differentiation agent which can induce complete remission in a majority of patients with acute promyelocytic leukemia (APL). Unfortunately, about one-fourth of patients thus treated may develop potentially fatal complications, including respiratory distress, fever, pericardial and pleural effusion, renal failure and hypotension which constitute the retinoic acid syndrome (RA syndrome). We report one APL patient, who presented with leukocytosis and subacute disseminated intravascular coagulopathy, and developed RA syndrome during treatment with ATRA. |
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