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題名 | Pregnancy Following Renal Transplantation=腎臟移植後之懷孕 |
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作者 | 石宏文; 張兆祥; 歐宴泉; 高育琳; 郭振華; 程千里; 楊啟瑞; | 書刊名 | 中華民國泌尿科醫學會雜誌 |
卷期 | 8:3 1997.09[民86.09] |
頁次 | 頁131-134 |
分類號 | 416.273 |
關鍵詞 | 賢臟移植; 懷孕; Renal transplantation; Pregnancy; |
語文 | 英文(English) |
中文摘要 | 從1982年10月至1996年10月,共有211個病患在本院接受腎臟移植。其中女性有96 個,而適孕女性( 20 ﹣ 40 歲)且移植腎功能良好之病患共有 47 位。 其中有 7 位患者 在 7 次成功的懷孕之後產下 8 個胎兒。所有的病患在懷孕過程當中都接受低劑量類固醇( prednisolone )之免疫治療,有 5 個病患合併接受環孢靈素( cyclosporin ),有 1 個 病患合併接受 azathioprine,有 1 個患者同時合併使用 prednisolone,cyclosporine 及 azathioprine 免疫藥劑。所有的胎兒都是自然生產。8 名胎兒中共有 5 個早產兒,所有的 胎兒都無先天畸型且體重與懷孕月份比都小於 50 %的生長曲線。 有 2 名病患有早期破水現象,有 3 名產婦有初期子癇( pre-eclampsia )有 1 名病患懷 孕中期產生移植腎水腫而需經皮腎造廔來保存腎功能。所有的病人在懷孕期間的腎功能都沒 有太大變化。因此我們認為只要密切的追蹤,對於接受腎臟移植的患者懷孕及生產仍是相當 安全的。 |
英文摘要 | A total of 211 kidney transplantations were performed at our hospital from Oct. 1982 to Oct. 1996. Of these available for this study, 96 were female and 47 were child-bearing age. A total of 7 patients with 7 successful pregnancies resulted in the birth of 8 infants (1 pair of twins). All the patients were maintained on low dose oral steroids throughout the pregnancy, 5 were on cyclosporine A, 1 on azathioprine and 1 on triple treatment. All births were completed with normal vaginal delivery. Premature birth occurred in 4 recipients (5 infants). All the babies were below the 50 percentile of the normogram of birth weight to gestational age. None had congenital abnormalities. Premature ruptures of membrane (PROM) occurred in 2 cases and pre-eclampsia occurred in 3 patients. One patient developed graft hydronephrosis in the 2nd trimester that needed PCN for renal function preservation. All of our patinets had stable renal function during the course of pregnancy. We conclude that pregnancy and delivery may not impose a significant threat to recipients and their graft kidneys if recipients are followed up regularly and carefully. |
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