頁籤選單縮合
題名 | Platelet Aggregation Inhibitor from Ganoderma Iucidum= |
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作者 | 吳天賞; 石麗仙; 郭盛助; 陳清玉; 董淑芳; 鄧哲明; Wu, Tian-shung; Shi, Li-shian; Kuo, Sheng-chu; Cherng, Ching-yuh; Tung, Shu-fang; Teng, Che-ming; |
期刊 | Journal of the Chinese Chemical Society |
出版日期 | 19970400 |
卷期 | 44:2 1997.04[民86.04] |
頁次 | 頁157-161 |
分類號 | 340 |
語文 | eng |
關鍵詞 | Ganoderma lucidum; Polyporaceae; Triterpenoids; Lucidenolactone; Antiplatelet aggregation; Single crystal x-ray structure; 2DNMR; |
英文摘要 | Tian-Shung Wu�W (吳天賞), Li-shian shi�z (石麗仙), Sheng-Chu Kuo(郭盛助), Ching-Yuh Cherng �W (陳清玉 ),Shu-Fang Tung �W (董淑芳 ) and Che-Ming Teng ( 鄧 哲明 ) �W Department of Chemistry, National Cheng Kung University, Tainan, Taiwan, R.O.C. �z Graduate Institute of Pharmaceutical Chemistry, China Medical College, Taichung, Taiwan, R.O.C. �z Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan, R.O.C. Lucidenic acid A (1) and a new lactone, lucidenolactone (2) were isolated from the fruiting bodies of Ganoderma lucidum. Their structures were elucidated by spectroscopic method and single-crystal X-ray analysis. Lucidenolactone (2) showed significant antiplatelet aggregation activity. The NMR spectral data of lucidenic acid A were also reassigned. |
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