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題名 | Congenital Rubella Syndrome after Maternal Reinfection: A Case Report=母體再次感染導致新生兒先天性德國麻疹症候群 |
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作者 | 凌大維; 李孝義; 韓志平; 嚴國棟; Lin, Da-wei; Lee, Shiaw-yih; Han, Chin-pine; Yan, Gwo-dong; |
期刊 | 中華民國婦產科醫學會會刊雜誌 |
出版日期 | 19970600 |
卷期 | 36:2 1997.06[民86.06] |
頁次 | 頁79-82 |
分類號 | 417.34 |
語文 | eng |
關鍵詞 | 母體再次感染; 新生兒先天性德國麻疹症候群; Maternal rubella reinfection; Rubella embryopathy; |
英文摘要 | 背景:德國麻疹的免疫經常被認為是終身的。但至今已有一些病例由於母體的再 次感染,導致新生兒先天性德國麻疹症候群。病例報告:本篇是描述一位第三胎的產婦,在 先前兩次懷孕的血清檢查發現已有德國麻疹抗體。這次在妊娠七週德國麻疹的血清效價為 1 :16。產婦在整個懷孕過程中,僅於妊娠六週時有輕微感冒症狀。三十八週時產下一女嬰, 由其臨床特徵及陽性德國麻疹血清 IgM 抗體得知女嬰罹患先天性德國麻疹症候群, 應由母 體再次感染所導致。結論:由於再次感染經常不會出現典型的症狀,而且抗體的變化也較緩 慢和不明顯,以致在懷孕早期很難想到是這類病患。所以即使產婦抗體為陽性,仍不能排除 其再次感染的可能。 ital rubella. Her rubella lgG titer rose to >500 lU/ml with enzyme-linked immunosobent assay during puerperium. The congenital rubella infection was proven with a high-titer rubella-specific IgM antibody in the serum of the infant and her ophthalmic and cardiac complications. Therefore, intrauterine transmission could have occurred after maternal reinfection during pregnancy. Conclusion: Congenital rubella following maternal reinfection has been described rarely. Previous immunity of rubella does not always indicate life-long immunity. Prenatal diagnosis after subclinical maternal reinfection is almost impossible. therefore, it is important to carefully investigate all women who have a high risk of contacting rubella. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。