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題名 | Hyperalimentation-Associated Hyperbilirubinemia in Pediatric Surgical Patients=小兒外科病患高濃度靜脈營養引發高血清膽紅素之分析 |
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作者 | 賴鴻緒; 虞希禹; 杜元超; 陳維昭; | 書刊名 | 中華民國外科醫學會雜誌 |
卷期 | 29:6 民85.11-12 |
頁次 | 頁468-473 |
分類號 | 417.56351 |
關鍵詞 | 小兒外科病患; 高濃度靜脈營養; 高血清膽紅素; Hyperalimentation; Hyperbilirubinemia; Risk factors; |
語文 | 英文(English) |
中文摘要 | 自1991年1月至1995年12月五年之間,台大醫院小兒外科病患共有72位患 者接受長期高濃度靜脈營養療法。其中有22位引發高血清膽紅素,占30.56。本論 文之目的,是分析這些病患中,引發高血清膽紅素者,與年齡、體重、疾病分類、 各種營養素含量、靜脈營養路徑、未進食及給予高濃度靜脈營養之期間長短、及 感染等因素之關係。結果發現,年齡小於兩個月者,有較高引發高血清膽紅素之 比率。高濃度靜脈營養給予及末進食期間在高血清膽紅素組(56.6±20.2天及30.2 ±9.6天)亦明顯比正常血清膽紅素組(29.1±12.9天及14.8±7.1天)長。中段腸道相 關疾病比率在高血清膽紅素組明顯較多。感染率在高血清膽紅素組病患亦明顯較 高。脂肪乳劑給予量,在高血清膽紅素組(2.25±0.63公克/公斤/日)比正常血清膽 紅素組(0.87±0.40公克/公斤/日)高。使用MVC 9+3(多含bintin、foIic acid,及維他 命B12)為維他命補充劑者,比使用一般MULTI VITA者,較不會引起高血清膽紅 素。體重、葡萄糖與氨基酸使用量、及靜脈營養路徑(中心成週邊靜脈)等因素, 在本研究中似乎與血清膽紅素之提高較無關。 |
英文摘要 | To evaluate the relationship between hyperbilirubinemia (HB) and hyperalimentation (HA) in pediatric surgical patients, seventy-two childrenreceiving long-term hyperalimentation nutritional support during theiradmission in surgical department, National Taiwan University Hospitalfrom January, 1991 to December, 1995 were reviewed retrospectively. Thepurpose of this study was to find out the relationship between hyperbilirubinemia and several possible risk factors. The incidence of hyperbilirubinemia was 30.56. Patients younger than two months old had ahigher incidence of HB. The average period for hyperalimentation and nothing per os (NPO) were significantly longer in HB group (56.6 ± 20.2 daysand 30.2 ± 9.6 days) than in the non-HB group (29.1 ± 12.9 days and 14.8±7.1days). The midgut-involved disease pattern was significantly more in theHB group than in the non-HB group. The infection rate was higher in theHB group than in the non-HB group. Fat supplement amount was larger inthe HB (2.25 ± 0.63 g/Kg/d) than in the non-HB group (0.87 ± 0.40 g/Kg/d).Patients receiving MVC 9+3 (biotin, folic acid, and vitamin-B12 included) asvitamin supplement source was associated with a lower incidence of HBthan those using MULTI VITA. Body weight, glucose amount or aminoacid amount in HA formula and HA route (central or peripheral) in thisstudy were not correlated with an HB condition. |
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