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題名 | Analysis of Donor Risk Factors in Acute Tubular Necrosis of Renal Allograft Recipients=腎臟移植後急性腎小管壞死之捐贈者危險因子之探討 |
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作者 | 胡瑞恆; |
期刊 | 中華民國外科醫學會雜誌 |
出版日期 | 19920500、19920600 |
卷期 | 25:3 民81.05-06 |
頁次 | 頁1153-1156 |
分類號 | 416.273 |
語文 | eng |
關鍵詞 | 腎臟移植; 急性腎小管壞死; |
中文摘要 | 為了探討腎臟移植後,發生急性腎小管壞死的可能捐贈者危險因子,我們對台大醫院自1988年1月至1990年12月所做之35例屍腎腎臟移植之捐贈者做一分析。35例中有12例在手術後發生急性腎小管壞死。我們探討捐贈者之5個可能因素:(1)捐贈者手術前是否有因心跳停止而需心肺復甦術急救;(2)病人是否需要大量之心臟加壓藥物以提昇血壓至90 mmHg;(3)是否因為尿崩之現象而使用Pitressin;(4)捐贈者手術前8小時之平均小便量;(5)整個手術之腎臟缺血時間。在這5項中,只有"合併使用多種心臟加壓藥物以提昇血壓"一項有臨床上及統計上的意義(P=0.034)。而心肺復甦術之有無、手術前之平均尿量以及腎臟缺血時間,雖有臨床上之差別,但統計上沒有意義(P值分別為0.163,0.220及0.09)。Pitressin之使用與否則完全沒有臨床上和統計上的差別(P=0.470)。 |
英文摘要 | For investigation of the possible donor risk factors for acute tubular necrosis (ATN) after renal transplantation, the 20 cadaver donors, whose kidneys were transplanted into 35 allograft recipients from January, 1988 to December, 1990, were studied in detail. The five possible donor risk factors studied included: 1) cardiopulmonary resuscitation during the preprocurement stage, 2) use of inotropic agents to keep blood pressure above 90 mmHg, 3) use of pitressin to combat the condition of preoperative polyuria, 4) average hourly urine output in the eight hours before organ procurement and 5) total ischemic time of the graft kidney. Only the use of combination of multiple inotropic agents has positive effect on the development of ATN after operation (P=0.034). Experience of CPR, average hour urine output, total ischemic time and the use of pitressin or not have no statistical difference (P=0.163, 0.220, 0.09 and 0.470 respectively). |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。