頁籤選單縮合
題名 | Mitomycin-C對血管增生性青光眼之效果=Effect of Topical Mitomycin-C in Neovascular Glaucoma |
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作 者 | 古婉珍; 賴旗俊; | 書刊名 | 中華民國眼科醫學會雜誌 |
卷期 | 35:1 1996.03[民85.03] |
頁次 | 頁21-26 |
分類號 | 416.748 |
關鍵詞 | 血管增生性青光眼; Mitomycin-c; Neovascular glaucoma; Trabeculectomy; |
語文 | 中文(Chinese) |
中文摘要 | Mitomycin-C併小樑切除術近幾年來已被廣泛的使用在各類青光眼的治 療。為了評估其使用在血管增生性青光眼的效果及安全性,我們收集了12個血管 增生性青光眼的病患共13隻眼,施以小樑切除術並輔以0.4 mg/cc的Mitomycin-C局 部敷用,術前有10眼接受全視網膜光凝固治療(PRP),二眼行全視網膜冷凍治療 (PRO),1眼無任何治療。追蹤6個月到30個月,其中10眼(77)眼壓在術後可控制在 21mmHg以下(包括2眼需要使用降眼壓藥物)。術後併發症中早期最常見的有前房 出血10眼,前房過淺2眼及前房有滲出物5眼。晚期併發症中,眼壓無法控制有3 眼,白內障加重有8眼,其中3眼到了完全白化的程度。根據本研究的結果, Mitomycin-C併小樑切除術使用於血管增生性青光眼是有效及安全的。 |
英文摘要 | Topical use of mitomycin-c intraoperatively atthe filtration site improved the surgical result offiltering operation. To evaluate the efFicacy and safetyof this procedure in patients with neovascularglaucoma, we collected 13 eyes of 12 patients, inwhom a 0.4 mg/ml solution of mitomycin-c wasapplied between tenon's capsule and the sclera,beneath partial thickness scleral flap, both for 5minutes during trabeculectorny. Most patients hadPRP or PRC before trabeculectorny. The follow-upperiod ranged from 6 to 38 months. Ten eyes (77)had an intraocular pressure of less than 21 mmHg with or without topical antiglaucoma medication (2with antiglaucoma medication). Three eyes (23)failed with maximal antiglaucoma medications. Nosignificant ocular toxicity from mitomycin-c wasobserved within this study. Post-op vision wasreduced in six eyes due to cataract, progression ofunderlying disease, or uncontrolled introacularpressure. The instances ofhyphema, shallow anteriorchamber, and hypotony were higher than usual. These results suggest that intraoperativeapplication of mitomycin-c is effective in neovascularglaucoma. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。