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題名 | Validation of Bioanalytical Method for Verapamil by Highperformance Liquid Chromatography=Verapamil之HPLC生物分析法的驗證 |
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作者 | 陳甘霖; 李芳裕; | 書刊名 | 醫學研究 |
卷期 | 17:1 1996.07[民85.07] |
頁次 | 頁16-23 |
分類號 | 414.7 |
關鍵詞 | 生物分析法; 驗證; Verapamil; Bioanalytical method; Validation; |
語文 | 英文(English) |
中文摘要 | 測定血中Verapamil含量HPLC之生物分析法須經驗證。血液中的Verapamil經抽取分離後,直接注入RP-18管柱分析定量之。此生物分析法之靈敏性、特異性、線性、準確性、精確性及試樣之安定性均經驗證後,確認適合作為Verapamil之生物分析法。 |
英文摘要 | A bioanalytical HPLC procedure for the determination of verapamil in plasma was validated. The plasma samples after extraction were analyzed by HPLC with RP-18 column. The method sensitivity, specificity, linearity, accuracy, precision, and sample stability were reported. The method was suitable for pharmacokinetic studies of verapamil. |
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