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題 名 | Osteosarcoma of Jaw: The Experience of Chang Gung Memorial Hospital=頷骨骨肉瘤: 長庚紀念醫院經驗 |
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作 者 | 陳仁熙; 廖宗琦; 王宏銘; 蔡銘修; 侯勝博; 薛綏; | 書刊名 | 長庚醫學 |
卷 期 | 18:3 1995.09[民84.09] |
頁 次 | 頁260-265 |
分類號 | 416.66 |
關鍵詞 | 骨肉瘤; 頷骨; Osteosarcoma; Jaw; |
語 文 | 英文(English) |
中文摘要 | 從民國72年1月到82年6月,長庚紀念醫院林口醫學忠心共有136例骨肉瘤患者,其中有7例(5%)是頷骨骨肉瘤患者;女性5位(71%),男性2位(29%),平均年齡為39歲。4例發生於下頷骨,3例發生於上頷骨。頷骨腫大為其主要症狀,而從症狀發生到診斷期間的3個月。X光上大多為骨溶病變。以病理學分類而言,4例為骨母細胞型,2例為軟骨母細胞型,及1例為毛細胞擴張型。7例中有6例接受手術治療,其中3例接受術後化學治療及放射治療,1例僅接受術後化學治療,及1例僅接受術後放射治療。但有1例因局部疾病太嚴重而沒有接受手術,僅接受姑息化學治。追踪至83年6月,4例死於局部疾病復發或治療併發症,但皆無全身轉移病灶(存活期從5個月至22個月)。3例存活,其中2例存活超過4年,中位存活期22個月。我們所得的結論是:頷骨骨肉瘤和一般長骨肉瘤的生物特性有所不同,而局部的復發是治療失敗的主因。 |
英文摘要 | Seven cases with Osteosarcoma (OS) of the jaw were retrospectively reviewed.There five female and two male patients. Their ages ranged from 14 to 57 years with a mean of 39 years. Seventy-one percent of the patients were older than 30 years old. Jaw swellings were the most frequent complaints occurring on an average of 3months before diagnosis. Four cases occurred in mandible and three cases developed from maxilla. Most cases were lytic lesions on roentgenography. Four were osteoblastic, 2 were chondroblastic, and 1 was telangiectatic by histologic classification. Six of the 7cases received surgery. Postoperatively. 3 of them received both radiotherapy and chemotherapy, 1 received chemotherapy only and 1 received radiotherapy only. One case received palliative chemotherapy only because of the locally far advanced disease. Four cases died or regional failure without any metastatic lesions (survival ranged from 5 months to 22 months). Two cases survived more than 4 years without any recurrence. The median survival time was 22 months. We concluded that OS of jaw has different natural courses from OS of the long bones and the regional failure seems to be the main problem in jaw OS. |
本系統中英文摘要資訊取自各篇刊載內容。