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題名 | 結膜黑色素瘤之臨床病理研究 |
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作者 | 王炳元; 高淑卿; 吳俊昇; 李鳳利; | 書刊名 | 中華民國眼科醫學會雜誌 |
卷期 | 31:3 1992.09[民81.09] |
頁次 | 頁63-69 |
分類號 | 416.741 |
關鍵詞 | 結膜惡性黑色素瘤; Conjunctival melanoma; Spitz nevus; Primary acquired melanosis; |
語文 | 中文(Chinese) |
中文摘要 | 我們報告三個結膜惡性黑色素瘤的臨床和病理表徵。第一個病例,在右 眼結膜上穹窿的黑色素增生範圍中,發現一個粉紅色小結,最初的病理診斷為 Spitz痣,然而在三年之間,多發性的粉紅色小結一再復發,且廣泛的色素病灶也 被發現。直到右側耳前淋巴結被惡性黑色素細胞浸潤,結膜惡性黑色素瘤才確認 診斷。六個月之後,發現全身性惡性細胞轉移。第二個病例,在下眼瞼結膜的黑 色素增生範圍中,發現一個黑色腫塊,病理檢查確定結膜惡性黑色素瘤,六個月 之後,因腫瘤增大及出血接受眼窩剜除術,術後一年病人仍存活。第三個病例, 在上眼瞼結膜發現黑色腫瘤,病人接受眼窩剜除術,術後檢查未發現全身系統性 惡性轉移。 本文中我們將討論兩個重點:1)結膜惡性黑色素瘤和Spitz痣二者應由臨床表徵和 病理發現來做鑑別診斷;2)原發性黑色素增生和結膜惡性黑色素瘤之間的關係。 |
英文摘要 | The chnicopathological manifestation of three cases of coruunctival melanoma was reported. In case1, a non-pigmentary pinkish nodule was noted in an area of melanosis over the right upper fornical conjunctiva. The pathological diagnosis of Spitz's nevus was made initially. Recurrences of multiple pinkish nodules and extensive pigmentary lesion were found during the period of three years. Malignant melanoma was not diagnosed until preauricular lymph node was infiltrated by malignent melanocytes. Six months later, the patient had systemic metastasis. In case 2, a heavy-pigmentary nodule in an area of melanosis over inferior palpebral conjunctiva was noted. Malignant melanorna was confirmed by pathology. Six months later, exenteration was performed due to enlargement and bleeding of the nodule. The patient still lives well. In case 3, a pigmentary nodule was found in an area of melaiiosis over conjunctiva. Exenteration was performed and no systemic metastasis was found postoperatively. Two points will be discussed: 1) the differential diagnosis between conjunctival melanoiiia and Spitz's nevus should be made according to clinic course and pathological finding; 2) melanosis ir.ay have the relationship with malignant melanonia 3) conjunctiva. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。