查詢結果分析
來源資料
相關文獻
- 去羧基凝血酶原之測定及其對肝疾病之診斷意義
- 血清膽汁酸分析在診斷肝膽疾病之探討
- AST/ALT 比值在診斷肝臟疾病之探討
- 胃腸道疾病在超音波診斷上的陷阱及其鑑別診斷
- 血清總膽汁酸對肝膽疾病之診斷價值
- 嬰兒稽延性阻塞性黃疸之研究(2):血清病麩胺轉肰酶(rGT) 活性測定對膽道閉鎖及新生兒肝炎鑑別診斷之評估
- α[feb5]胎兒蛋白對肝疾病診斷之價值
- 慢性活動性肝疾病--定義、診斷及治療
- 慢性阻塞性肺部疾病患者肺功能狀態與中醫證型及舌診影像科學化研究之關係
- Reliability of HDRS and HARS Telepsychiatric Assessment of Anxiety and Depression
頁籤選單縮合
題名 | 去羧基凝血酶原之測定及其對肝疾病之診斷意義 |
---|---|
作者姓名(中文) | 何照洪; | 書刊名 | 醫學研究 |
卷期 | 8:6 1988.05[民77.05] |
頁次 | 頁397-404 |
分類號 | 415.145 |
關鍵詞 | 去羧基凝血酶原; 肝; 疾病; 測定; 診斷; |
語文 | 中文(Chinese) |
中文摘要 | 以一簡單的實驗室方法,測定255位血漿去羧基凝血原(DCP)。其中59位為健康常人,100位為原發性肝細胞癌,33位為肝硬變,16位為肝炎,11位為轉移性肝癌及36位為服用抗維生素K藥物之患者。健康常人之DCP值在0-6VGH u/l之間(平均值為3.02 VGH u/l);而服用抗維生素K之病患之DCP值在73-323 VGH u/l之間(平均為2/4.20 VGH u/l)。若以DCP值大於10 VGH u/l為不正常,則有約62%肝癌病患,其DCP值不正常。在良性之肝硬變及肝炎患者中,其DCP值均為正常;而在轉移性肝症之病患中,有36.36%具不正常之DCP值。由以上資料顯示,良性之肝疾病患者,無一人有高DCP值者。因此,當一位病人具有正常之DCP值時,雖然不能排除其肝癌之可能性,但當在一臨床上診斷為良性肝病而具有高DCP值之病人中,應高度懷疑已有肝癌之可能性,此亦為DCP在臨床上之重診斷特性及價值。 |
英文摘要 | A simple a practical laboratory method to assay plasma des-gamma-carobxyprothrombin (DCP) was applied in 255 subjects. Among them, 59 were healthy subjects, 100 had primary hepatocellular carcinoma (PHC), 33 had cirrhosis of liver, 16 had hepatitis, 11 had metastatic carcinoma of liver, and 36 subjects previously treated with antivitamin K drugs. The mean plasma DCP level in the healthy subjects was 3.02 VGH u/l (0 to 6 VGH u/l), while the mean DCP level in the patients treated with antivitamin K drugs was 214.2 VGH u/l (73-323 VGH u/l). 62% of the patients with PHC had DCP levels over 10 VGH u/l which we regarded as abnormal. On the other hand, none of the patients having benign liver disease (cirrhosis of liver or hepatitis) had abnormal DCP. In the patients with metastatic carcinoma of liver, 36.36% had abnormal DCP level. From these data, we found that none of the subjects having benign liver diseases had high DCP level. Thus, though we can not rule out the possibility of PHC in a patient with normal DCP, we should always suspect a patient of benign liver disease but with high DCP to be probable PHC. This is an important characteristic of DCP on the diagnostic value of PHC. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。