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- Hyperbaric Oxygen Therapy in the Treatment of Chronic Refractory Osteomyelitis: A Preliminary Report
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- Adjuvant Hyperbaric Oxygen Therapy in the Treatment of Chronic Refractory Osteomyelitis: A Preliminary Report
- Results of Chronic Osteomyelitis of the Femur Treated with Hyperbaric Oxygen: A Preliminary Report
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頁籤選單縮合
題名 | 高壓氧治療與慢性骨髓炎= |
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作者 | 熊震宇; 謝學法; 魏華儀; |
期刊 | 醫學研究 |
出版日期 | 19870500 |
卷期 | 7:6 1987.05[民76.05] |
頁次 | 頁309-316 |
分類號 | 416.26 |
語文 | chi |
關鍵詞 | 治療; 氧; 骨髓炎; 高壓; 慢性; |
中文摘要 | 本院自1976年至1984年以高壓氧配合外科手術及抗生素治療了112位慢性骨髓炎的病人。本文所收集之病患必須合乎四個條件:(1)骨髓炎患病期(duration)至少三個月,(2)接受高壓氧之前,為了治療骨髓炎至少接受過一次手術治療,(3)必須接受過非腸道吸收的抗生素治療,(4)高壓氧治療完結以後,至少追踪兩年以上。本文報告82例合乎上述條件者,平均追踪49.6個月,其中74例臨床上沒有復發現象,臨床緩解率(remission rate)達90.2%。失敗病例顯示和慢性程度(chronicity)及高壓氧治療前手術次數(times of previous surgery)有關(P<0.05);另外產生再骨折(refracture)的三例病人全都復發骨髓炎,顯示強直固定及避免再骨折在整個治療過程中是極為重要的。 慢性骨髓炎的治療經常復發,給病人帶來一連串的困擾,本文初步結果顯示高壓氧可以配合外科手術及抗生素來有效的治療慢性骨髓炎。 |
英文摘要 | Between 1976 and 1984, 112 patients with chronic osteomyelitis have been treated with hyperbaric oxygen as an adjunct to surgical therapy and antibiotics at Kee-Lung Naval Hospital. 82 patients included in this study, the patient must: (1) have had the infection for at least 3 months, (2) have undergone at least one surgical procedure, (3) have been treated with parenteral antibiotics, and (4) have a minimum follow-up of two years following our combined treatment regimen. Of these 82 patients, 74 patients (90.2%) remain free of clinical sign of osteomyelitis after an average of 49.6 months follow-up. The recurrence seems to be related to chronicity of the infection and times ot previous surgical procedures, (p<0.05). All of the three cases of refracture following treatment got recurrence, we believe that rigid fixation and refrature prevention were the most important principle of treatment. In spite of these encouraging results, we are careful not to term these cases cured of their chronic osteomyelitis. A much longer follow-up is essential before a true cure rate can be determined. We believe that hyperbaric oxygen therapy is indicated as an adjunct to improve results of surgical-antibiotic treatment plans in patients with chronic osteomyelitis in which other treatment modalities have failed. |
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