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題名 | 精神分裂症患者血清麩氨草酸轉胺酶之變化= |
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作者 | 沈君傑; 林玉財; |
期刊 | 醫學研究 |
出版日期 | 19841000 |
卷期 | 5:4 1984.10[民73.10] |
頁次 | 頁2055-2059 |
分類號 | 415.983 |
語文 | chi |
關鍵詞 | 血清氨草酸麩轉胺酶; 精神分裂症患者; |
中文摘要 | 102名精神分裂症住院患者(男:85名,女:17名,平均年齡:24.65±7.75歲)及87名非精神病患者(均為男性,平均年齡:24.24±8.58歲)於住院第一天清晨抽血測定其血清麩氨草酸轉胺酶(serum glutamic oxaloacetic transaminase, SGOT)之值。精神分裂組其SGOT升高者(>40µ/ml)有12名(佔11.76%),其SGOT平均值為25.66±1.48µ/ml。非精神病組其SGOT升高者有2名(佔2.30%),其SGOT平均值為21.40±0.88µ/ml。結果顯示精神分裂組其SGOT升高之人數比例較非精神病組者為高(P<0.01),且前組之SGOT平均值亦較後組者為高(P<0.02)。又精神分裂組中,SGOT平均值之高低與患者活動量之高低成就有意義之相關性(P<0.0025),而與幻聽,妄想及思考不連貫等主要精神症狀無相關性。精神分裂組亞型中其他型精神分裂症(緊張型、單純型、情感型、未分類型)其SGOT升高之人數比例較妄想型及青春型精神分裂症者為高(P<0.05),而三者之SGOT平均值之高低則無顯著之差異。精神分裂組中,SGOT升高之人數比例及SGOT平均值之高低與發病時間長短無顯著之相關性。 |
英文摘要 | SGOT (Serum glutamic oxaloacetic transaminase) was measured in 102 schizophrenic inpatients (M:85, F:17, mean age: 24.65±7.75) and 87 non-psychotic inpatients (all males, mean age: 24.24±8.85) in their first morning of hospitalization. 12 shizophrenics (11.7%) and 2 non-psychotics (2.30%) had elevated SGOT (40U/ml), the mean value being 25.66±1.48 and 21.40±0.88U/ml respectively. Both the percentage of elevation and the mean value of SGOT were significantly higher in schizophrenic group than that in non-psychotic group (P<0.01 & P<0.02). In schizophrenic group, the elevation of SGOT was significantly correlated with the degree of degree of activity (P<0.0025) but not so with hallucination, delusion and disturbance of association. Divided by the subgroup of schizophrenia, the percentage of elevation of SGOT in other type (catatonia, simple, schizoaffective & undifferentiated) was significantly higher than that of paranoid & hebephrenic (P<0.5). The mean value of SGOT in each subgroup had no significant difference. In addition, both the percentage of elevation and the mean value of SGOT had no significant correlation with the duratin of the psychoses. |
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