頁籤選單縮合
題名 | Rapid Progression of Diffuse Parenchymal Lung Disease in a Woman with Dual Positives of Anti-MDA-5 and Anti-RO-52 Amyopathic Dermatomyositis, Resulting in Refractory Hypoxemia and Death following Surgical Lung Biopsy: A Case Report and Literature Review |
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作者姓名(中文) | |
作者姓名(外文) | Chen, Chi-en; Lee, Chih-hsin; Chen, Lung-fang; Chang, Yin-chun; |
書刊名 | 胸腔醫學 |
卷期 | 39:1 2024.03[民113.03] |
頁次 | 頁91-98 |
分類號 | 416.224 |
語文 | eng |
關鍵詞 | Amyopathic dermatomyositis; Anti-MDA-5 antibodies; Diffuse parenchymal lung disease; Video-assisted thoracoscopic surgical lung biopsy; Transbronchial lung cryobiopsy; Organizing pneumonia; |
英文摘要 | A 55-year-old female presented with Gottron's papule, mechanic's hands, and periungual erythematous change. She was diagnosed with amyopathic dermatomyositis with positive anti-MDA-5 and anti-RO52 antibodies. Despite aggressive immune-modifying therapy and comprehensive antimicrobial treatment, she developed rapidly progressive diffuse parenchymal lung disease following a surgical biopsy that resulted in refractory hypoxemia and death. We performed a literature review and scrutinized the clinical course for possible etiologies of the devastating complications following surgical biopsy in our patient. We found that transbronchial lung cryobiopsy, an emerging novel technique, could be a potential diagnostic alternative to surgical lung biopsy to avoid postoperative morbidities and mortalities in patients with amyopathic dermatomyositis with diffuse parenchymal lung disease. |
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