頁籤選單縮合
題名 | Variation in Oxygen Saturation Measured by a Wearable Device May Predict Response to Treatment in Patients with Community-Acquired Pneumonia= |
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作者 | Wu, Yu-cheng; Huang, Chien-chung; Hsu, Chiann-yi; Chao, Wen-cheng; Wu, Chieh-liang; |
期刊 | 胸腔醫學 |
出版日期 | 20240300 |
卷期 | 39:1 2024.03[民113.03] |
頁次 | 頁13-23 |
分類號 | 415.463 |
語文 | eng |
關鍵詞 | Pneumonia; Pulse oximetry; Internet of things; IoT; Wireless; Monitoring; |
英文摘要 | Background: Community-acquired pneumonia (CAP) is 1 of the leading causes of death worldwide, and early prediction of response to treatment is crucial in managing patients with CAP. Wearable devices are increasingly being used to monitor physiological parameters continuously. Therefore, the aim of this study was to determine the ability of wearable devices to predict the outcome of treatment for patients with CAP. Methods: We prospectively enrolled patients with CAP at a tertiary referral hospital in central Taiwan between 2020 and 2021, and used wearable devices to monitor oxygenation (SpO2) and physical activity for 2 days after admission. An unfavorable treatment outcome on Day 5 was determined by clinical deterioration, radiographic progression, or pneumonia-related complications. Multivariate logistic regression was used to determine the odds ratio (OR) and 95% confidence interval (CI). Results: A total of 62 patients with CAP were enrolled, and 51.6% (32/62) of them were classified as having unfavorable treatment outcomes. The groups with favorable and unfavorable treatment outcomes had similar disease severities, including CURB-65 (1.13±0.82 vs. 1.06±0.8, p=0.719) and the pneumonia severity index (97.3±36.21 vs. 98.06±31.7, p= 0.983). We found a lower SpO_2, a higher variation in SpO_2, and lower physical activity in those with an unfavorable response compared to those with a favorable response. After adjusting for age, sex, and severity, we found that a lower average SpO_2 (OR: 0.91, 95% CI 0.62-1.33, P=0.624) and a greater variation in SpO_2 (OR: 1.87, 95% CI 1.02-3.42, P=0.044) on Day 2tended to be associated with an increased risk of an unfavorable treatment outcome. Conclusion: In this study, we continuously monitored CAP patients using a wearable device and identified Day 2 SpO2 average and variation as potential early treatment outcome predictors. |
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