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題名 | One-year Outcomes of a Suture-less Laparoscopic Sacral Hysteropexy Using Polypropylene Y-mesh Grafts and Fibrin Sealant Spray: A Prospective Comparative Study= |
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作者 | Tsai, Ching-pei; Kao, Hui-fen; Liu, Chih-ku; Shen, Pao-sheng; Chen, Ming-jer; Hung, Man-jung; |
期刊 | Journal of the Chinese Medical Association |
出版日期 | 20200500 |
卷期 | 83:5 2020.05[民109.05] |
頁次 | 頁484-490 |
分類號 | 417.281 |
語文 | eng |
關鍵詞 | Fibrin sealant; Lightweight polypropylene meshes; Sacral hysteropexy; Uterine preservation; Uterovaginal prolapse; |
英文摘要 | Background: Laparoscopic sacral hysteropexy (SH) is a minimally invasive and effective treatment for uterovaginal prolapse in women who wish to retain the uterus. However, this procedure is limited by a steep learning curve and a long operating time. In this study, we aim to evaluate the surgical outcomes of a modified laparoscopic SH procedure using innovative methods of vaginal mesh attachment, which we hypothesized to be equally effective and time-saving. Methods: This was a prospective, parallel, comparative study conducted at a tertiary referral hospital. A total of 34 women with advanced (POPQ [Pelvic Organ Prolapse Quantification] stages ≧ 2) uterine prolapse, who underwent a laparoscopic SH procedure using lightweight polypropylene Y-mesh grafts (ALYTE), were studied. In half (n = 17) of the cases, fibrin sealant spray (TISSEEL) was applied to the meshes fixed at the anterior and posterior vaginal wall with fewer (six vs at least ten) sutures. A detailed comparison of one-year outcomes between groups was performed. Results: Patient characteristics and perioperative results were comparable between groups with the exception of a significantly shorter total operating time (247.0 vs 292.9 minutes, p = 0.04) noted in the fibrin group. At 1 year, anatomic success (POPQ stage ≦1) rates (76.5% vs 76.5%) were not different between groups. There were eight patients, with four in each group, who had surgical failure. Notably, most (7/8; 87.5%) surgical failures were at the anterior compartment (i.e, recurrent cystocele). No vaginal mesh extrusions were noted. After statistical analysis, we found “cystocele as the dominant prolapse before operation” was a significant predisposing factor for prolapse recurrence (p = 0.019; odds ratio = 8.04). Conclusion: The modified laparoscopic SH procedure using Y-mesh grafts and fibrin sealant spray with fewer vaginal sutures was equally effective as conventional methods but saved time. Laparoscopic SH using Y-mesh grafts might not be as effective in repairing a concomitant dominant cystocele. |
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