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題名 | 2018年新生兒伊科11型腸病毒重症案例報告=Severe Echovirus 11 Infection in Newborns, Taiwan, 2018 |
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作者 | 蘇韋如; 黃婉婷; 鄭皓元; 魏欣怡; | 書刊名 | 疫情報導 |
卷期 | 34:21 2018.11.06[民107.11.06] |
頁次 | 頁336-340 |
分類號 | 417.516 |
關鍵詞 | 伊科病毒11型; 腸病毒重症; 新生兒; 肝炎; 瀰漫性血管內凝血不全; Echovirus 11; Severe enterovirus infection; Neonate; Hepatitis; Coagulopathy; |
語文 | 中文(Chinese) |
中文摘要 | 2018年5月起,疾病管制署陸續接獲新生兒腸病毒重症個案通報,截至7月底已確診8例伊科11型腸病毒重症個案(7例死亡),其臨床表現主要為肝炎合併凝血功能異常與敗血症。伊科11型腸病毒可能透過胎盤、生產過程或產後接觸傳染給新生兒而導致重症,醫師診治新生兒若發現心肌炎、肝炎、腦炎、血小板下降、敗血症、或多重器官衰竭等徵象,排除細菌等其他常見病原感染時,需高度懷疑為新生兒腸病毒重症;產婦除懷孕期間、生產前做好手部及呼吸道衛生外,產前14天至分娩後如本人或家中幼童出現發燒等症狀,應告知醫師;家中成人或幼童如有身體不適,應避免接觸新生兒;醫療院所及產後護理之家等機構則應落實感染管制措施,避免疫情擴散。 |
英文摘要 | Beginning May 2018, Taiwan Centers for Disease Control was notified of an increase in reports related to severe enterovirus (EV) infection in newborns. Through July 31, severe echovirus 11 infections were confirmed in eight neonatal patients (5 males, age 0–12 days). Clinical presentations included hepatitis with coagulopathy (n = 8), sepsis syndrome (n = 8), myocarditis (n = 2), and multiorgan dysfunction (n = 7); 7 (87.5%) died. Neonatal echovirus 11 infections may be acquired transplacentally, during delivery, or from postnatal transmission, and are associated with severe complications. Clinicians should consider and report severe EV infection in neonates having myocarditis, hepatitis, encephalitis, thrombocytopenia, sepsis syndrome, or multiorgan dysfunction, but with sterile bacterial cultures. In EV epidemic seasons, we recommend appropriate hand and respiratory hygiene of pregnant women; obstetric notification of fever and other illness from 14 days before delivery; keeping sick people away from a newborn; and infection controls in healthcare/postpartum care facilities. |
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