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題名 | 富含n-3多元不飽和脂肪酸之藻油補充品對於使用化放療頭頸癌患者之影響--病例報告=The Effect of n-3 PUFA-rich Algal Oil Supplementation in a Head and Neck Cancer Patient during CCRT: Case Report |
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作者 | 邱子涵; 蔡宛芮; 侯沂錚; Chiu, Tzu-han; Cai, Wan-ruei; Hou, Yi-cheng; |
期刊 | 臺灣營養學會雜誌 |
出版日期 | 20190600 |
卷期 | 43:2 2019.06[民108.06] |
頁次 | 頁47-56 |
分類號 | 411.3 |
語文 | chi |
關鍵詞 | 頭頸癌; 素食; 藻油; n-3多元不飽和脂肪酸; Head and neck cancer; Vegetarian; Algal oil; n-3 fatty acid; |
中文摘要 | 放射線與化療是常見之頭頸癌療程之一,放化療期間增加n-3多元不飽和脂肪酸(n-3 poly-unsaturated fatty acids, n-3 PUFAs)之攝取,可以幫助降低體內之發炎反應,素食來源之藻油富含n-3多元不飽和脂肪酸,本篇將討論藻油對接受合併化放療頭頸癌病患的影響。本個案為1位59歲女性,鼻咽癌第2期(cT1N1M0, stage II),接受放療合併化學治療。個案茹素多年。在營養師營養介入前,個案之白蛋白及C-反應蛋白指數皆屬於正常值間。個案因即將放化療,故給予化療期間營養注意事項衛教及n-3多元不飽和脂肪酸對於治療期間之影響,且願意使用藻油補充品。經營養介入後,個案之白蛋白指數維持正常,C-反應蛋白上升減少,減輕之體重小於文獻中之10%,顯示藻油能維持頭頸癌病患之整體營養狀況。 |
英文摘要 | Radiotherapy and chemotherapy are common head and neck cancer regimens. Increasing the intake of n-3 polyunsaturated fatty acids (PUFAs) during radiotherapy and chemotherapy can reduce inflammation. Algal oil is a vegetarian product and is rich in n-3 PUFAs. We discuss the effect of algal oil supplementation in head and neck cancer patients during [?]continuous renal replacement therapy (CRRT). This case was a 59-year-old woman with stage II nasopharyngeal carcinoma (NPC) receiving radiotherapy and chemotherapy. She had been a vegetarian for many years. Before the dietitian's nutrition intervention, albumin and C-reactive protein (CRP) were in normal ranges. Before radiotherapy and chemotherapy, she agreed to receive nutritional education about the effects of n-3 PUFAs during chemotherapy and used a vegetarian source of an n-3 PUFA supplement. Following a sustained nutritional intervention, albumin remained in a normal range, the increase in CRP was reduced, and weight loss was less than 10% that described in the literature. This case report indicates that the algal oil supplementation can maintain the nutritional status in head and neck cancer patients during CRRT. |
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