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頁籤選單縮合
題名 | 淺談酒渣鼻=Rosacea |
---|---|
作者姓名(中文) | 楊璦瑜; 蘇玉惠; 郭震羣; | 書刊名 | 藥學雜誌 |
卷期 | 33:1=130 2017.03[民106.03] |
頁次 | 頁23-28 |
分類號 | 415.7 |
關鍵詞 | 四環素; Rosacea; Brimonidine; Metronidazole; |
語文 | 中文(Chinese) |
中文摘要 | 酒渣鼻 (rosacea) 是一種慢性發炎的皮膚疾病,常見的症狀為臉部紅斑、臉部 毛細血管擴張、皮膚發炎症狀。特徵是病情發作與緩解反復的發生,難以完全治 療。根據症狀將酒渣鼻分類為 erythematotelangiectatic (ETR)、papulopustular (PPR)、 phymatous、ocular。數種酒渣鼻的誘發因子已被發現,包括辛辣食物、熱飲、酒 精、日曬、運動、壓力、nitroglycerin、calcium channel blocker 等。研究顯示治療 持久性紅斑最有效的藥物為外用 brimonidine。輕微到中度病情的患者可使用外用 metronidazole、azelaic acid、ivermectin 或 sulfacetamide-sulfur。四環素藥物是酒渣鼻 的標準全身治療藥物。同時考量病人教育、皮膚護理,非藥物與藥物治療才是對病人 最有效的治療。治療目標為症狀控制和提高生活品質。 |
英文摘要 | Rosacea is a chronic inflammatory skin condition. Common features including facial erythema, telangiectasias, and inflammatory skin lesions. It characterized by recurrent episodes of exacerbation and remission. Classification of rosacea includes erythematotelangiectatic (ETR), papulopustular (PPR), phymatous and ocular subtypes by symptoms. Various causes have been found to act as aggravation factors of rosacea, such as spicy food, hot drinks, alcohol, sun exposure, exercise, stress, nitroglycerin, Calcium channel blocker. The pharmacologic agent with the evidence for efficacy for persistent facial erythema in rosacea is topical brimonidine. Patients with mild to moderate disease can be managed with topical therapies such as metronidazole, azelaic acid, topical ivermectin, or sulfacetamide-sulfur. And tetracyclines are the standard systemic therapy of rosacea. Patient education, skin care, nonpharmacologic and pharmacologic treatments are all pillars of effective and comprehensive management of rosacea. Treatment goals are better symptom control and improved quality of life for individuals. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。