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題名 | Intralesional Curettage of Central Low-Grade Chondrosarcoma: A Midterm Follow-up Study |
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作者 | Chen, Yi-chou; Wu, Po-kuei; Chen, Cheng-fong; Chen, Wei-ming; | 書刊名 | Journal of the Chinese Medical Association |
卷期 | 80:3 2017.03[民106.03] |
頁次 | 頁178-182 |
分類號 | 416.66 |
關鍵詞 | Extended curettage; Low-grade chondrosarcoma; Wide excision; |
語文 | 英文(English) |
英文摘要 | Background: The aim of this study was to review the experience of surgical treatment of low-grade chondrosarcoma and to assess the long-term oncological and functional outcomes between intralesional curettage and wide excision. Methods: We included 11 patients with central low-grade chondrosarcoma lesions treated with intralesional curettage or wide excision from 1998 to 2013. Seven patients were treated with intralesional curettage and local adjuvant treatment (Group A), and four patients were treated with wide excision and reconstructive surgery (Group B). The mean age of patients was 43.8 ± 17.6 years (range, 20e71 years), and the mean duration of follow-up was 84.4 ± 47.6 months (range, 48e194 months). Results: Group A had a significantly lower complication rate than Group B; three complications were documented in Group B (0% vs. 75%, p ¼ 0.024). The operative time (177.1 hours vs. 366.3 hours, p ¼ 0.010) and the hospital stay (6.6 days vs. 12.5 days, p ¼ 0.010) were significantly shorter in Group A. There was one local recurrence in Group A without statistical significance. Also, there were no differences between intralesional curettage and wide excision with respect to the blood loss. No metastasis disease occurred in either group during the follow-up period. The Musculoskeletal Tumor Society (MSTS) scores in Groups A and B were 99.0 ± 2.5 and 94.2 ± 4.2, respectively, with statistically significant difference ( p ¼ 0.048). Conclusion: Extended intralesional curettage has the benefits of good MSTS score, shorter operative time, shorter hospital stay, and lower complication rate without increasing local recurrence in central low-grade chondrosarcoma. For central low-grade chondrosarcoma, we suggest extended curettage to decrease soft tissue damage and surgical risk. |
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