頁籤選單縮合
題名 | Accelerate Regression of Uremic Tumoral Calcinosis by Non-Calcium Phosphate Binder |
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作者 | Yan, Ming-tso; Chen, Yi-ann; De Broe, Marc E.; Yang, Chwei-shuin; | 書刊名 | 臺灣腎臟醫學會雜誌 |
卷期 | 29:3 2015.09[民104.09] |
頁次 | 頁169-175 |
分類號 | 415.816 |
關鍵詞 | Lanthanum carbonate; Parathyroidectomy; Tumoral calcinosis; |
語文 | 英文(English) |
英文摘要 | Uremic tumoral calcinosis (UTC) is an uncommon but treatable complication of mineral metabolism in dialysis patients although management is challenging. We reported two cases with end stage renal disease receiving respectively hemodialysis (10 years) and peritoneal dialysis (6 years). UTC developed in both cases with hyperphosphatemia, eucalcemia and secondary hyperparathyroidism. Progression of UTC persisted in both patients despite medical therapy including adequate dialysis, dietary phosphate restriction, calciumbased phosphate binders and calcitriol. After parathyroidectomy (PTx), resolution of UTC was limited in both patients 14 months and 24 months after surgery, respectively. Considering positive calcium balance in chronic dialysis patients using calcium-based phosphate binders, lanthanum carbonate (LC), a non-calciumcontaining phosphate binder, was used. UTC was rapidly resolved in both patients 1 month and 5 months later, respectively. The mechanism behind the rapid resolution of UTC after using LC is discussed. |
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