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題名 | 利用同步化放療治療食道類淋巴上皮癌--病例報告=Lymphoepthelioma Like Carcinoma (LELC) of the Esophagus Treated with Concurrent Chemoradiotherapy--A Case Report |
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作者姓名(中文) | 葉啟源; 賴鵬安; 劉芳慧; 曹唐義; | 書刊名 | 放射治療與腫瘤學 |
卷期 | 23:2 2016.06[民105.06] |
頁次 | 頁123-128 |
分類號 | 416.216 |
關鍵詞 | 淋巴上皮癌; EB病毒; 食道; 同步化放療; Lymphoepithelioma; Epstein-Barr virus; Esophagus; Concurrent chemoradiotherapy; |
語文 | 中文(Chinese) |
中文摘要 | 原發性食道類淋巴上皮癌(LELC)是一種非常罕見的疾病,在醫學文獻只有29例報導的案例。此腫瘤的特徵是未分化細胞混合有緻密的淋巴細胞浸潤,在多數文獻報告中指出和EBV的DNA相關。在本篇報告中提出一名52歲的男性患者被診斷為第四期(cT3N2M1)食道中下段LELC,到院時主訴有3個星期的時間吞嚥困難。該患者利用同步化療和放射治療(CCRT)治療成功。治療後12個月對食道再進行一次切片顯示腫瘤完全緩解,追蹤24個月病患仍然存活且沒有復發,目前仍繼續門診追蹤。 |
英文摘要 | Primary lymphoepithelioma like carcinoma (LELC) of the esophagus is a very rare disease; only 29 cases were reported in the medical literature. This type of tumor is characterized by undifferentiated cells mixed with dense lymphocytic infiltration. Here we would like to present a 52 year old male patient who was diagnosed with stage IV (cT3N2M1) LELC of the middle to lower esophagus. The patient's chief complaint was dysphagia of 3 weeks duration. The patient was successfully treated with concurrent chemotherapy (PF4 regimen) and radiotherapy (5040 cGy). A repeat esophageal biopsy done 12 months after concurrent chemoradiation therapy (CCRT) revealed no evidence of tumor. This patient is alive and disease-free 24 months after CCRT. |
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