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題名 | 單管照射與四照野假體照射應用於凝膠劑量計之分析=Single-Tube Irradiated and Phantom Irradiated in Four Fields Applied to the Analysis of Gel Dosimeter |
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作者姓名(中文) | 邱琮祐; 謝栢滄; 張淵仁; 趙璽雅; 邱琮祐; 謝栢滄; | 書刊名 | 中華放射線技術學雜誌 |
卷期 | 40:1 2016.03[民105.03] |
頁次 | 頁34-40 |
分類號 | 416.14 |
關鍵詞 | 聚合凝膠劑量計; 電腦斷層掃描儀; 劑量解析度; Polymer gel dosimeter; Computer tomography; Dose resolutions; |
語文 | 中文(Chinese) |
中文摘要 | 近年來聚合凝膠劑量計被廣泛的研究,它是唯一能提供三維劑量分佈的劑量量測工具,在接受射輻射照射後,可依其聚合反應程度之不同來推估其所接受之劑量,並利用電腦斷層掃描儀來獲取凝膠影像資訊。而異丙基丙烯醯胺(N-isopropylacrylamide, NIPAM dosimeter)凝膠劑量計是以NIPAM為單體的凝膠劑量計(gel dosimeter),此凝膠最大特點是其毒性低,並且可以在正常大氣壓力狀況(normal atmospheric conditions)下製備。本研究目的是利用凝膠假體照射方式去取代傳統單管凝膠照射法來獲取凝膠劑量反應曲線,以評估在臨床使用之可行性。研究結果顯示,凝膠在接受了0-8Gy劑量後,單管凝膠照射法與凝膠假體照射法皆可獲得高線性度之劑量反應曲線,其R^2分別為0.997與0.982,而在凝膠特性上,劑量敏感度(dose sensitivity)反應分別為0.699與0.754CTN/Gy,相對劑量解析度(relative dose resolution)分別為0.55Gy及0.68Gy。因此,對於凝膠假體照射方式來獲取凝膠劑量反應曲線之方式,可作為後續大體積凝膠於複合照野照射時校正曲線之用。凝膠劑量計為一組織等效(tissue equivalent)的輻射劑量計(其有效原子序為7.62),不必經由複雜修正即可使用,因此可提高了臨床使用性。 |
英文摘要 | Polymer gpolymer gel dosimeter has been extensively studied in recent years. It is the only measured tool to provide a three-dimensional dose distribution using computer tomography to obtain gel image information by different degrees of polymerization reaction and evaluate absorbed dose after irradiation. The low toxic N-isopropylacrylamide (NIPAM) dosimeter, which can be prepared under normal atmospheric conditions, is one of the most common gel dosimeters polymerized by NIPAM monomers. The purpose of this study is to assess the feasibility using the gel in phantom irradiated with radiation to replace the traditional single-tube gel to obtain gel dose-response curves in the clinical application. The results showed that single-tube gel and the gel in phantom irradiated both obtain high linearity of dose-response curve after irradiated dose of 0-8Gy and the R^2 was 0.997 and 0.982, respectively. The properties of gel dosimeter are similar while dose sensitivities were 0.699, 0.754CTN/Gy and the relative dose resolutions were 0.55Gy, 0.68Gy. Thus the gel in phantom can be used as a large volume of gel to get a dose-response curve for subsequently calibration curve of complex fields. Gel dosimeter is a tissue-equivalent dosimeter (the effective atomic number is 7.62) for radiation without a complicated correction therefore gel dosimeter can improve the clinical usability.el dosimeter has been extensively studied in recent years. It is the only measured tool to provide a three-dimensional dose distribution using computer tomography to obtain gel image information by different degrees of polymerization reaction and evaluate absorbed dose after irradiation. The low toxic N-isopropylacrylamide (NIPAM) dosimeter, which can be prepared under normal atmospheric conditions, is one of the most common gel dosimeters polymerized by NIPAM monomers. The purpose of this study is to assess the feasibility using the gel in phantom irradiated with radiation to replace the traditional single-tube gel to obtain gel dose-response curves in the clinical application. The results showed that single-tube gel and the gel in phantom irradiated both obtain high linearity of dose-response curve after irradiated dose of 0-8Gy and the R^2 was 0.997 and 0.982, respectively. The properties of gel dosimeter are similar while dose sensitivities were 0.699, 0.754CTN/Gy and the relative dose resolutions were 0.55Gy, 0.68Gy. Thus the gel in phantom can be used as a large volume of gel to get a dose-response curve for subsequently calibration curve of complex fields. Gel dosimeter is a tissue-equivalent dosimeter (the effective atomic number is 7.62) for radiation without a complicated correction therefore gel dosimeter can improve the clinical usability. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。