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頁籤選單縮合
題名 | 腎臟移植後的Kaposi Sarcoma=Kaposi Sarcoma in Renal Transplantation |
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作者姓名(中文) | 魏廷聿; 葉子慧; 王台欣; | 書刊名 | 藥學雜誌 |
卷期 | 31:3=124 2015.09[民104.09] |
頁次 | 頁76-79 |
分類號 | 415.641 |
關鍵詞 | 腎臟移植; 人類疱疹病毒第8型; Kaposi sarcoma; HHV-8; |
語文 | 中文(Chinese) |
中文摘要 | Kaposi sarcoma 為器官移植後相關併發症之一,常見於腎臟移植病人,一般認 為與免疫抑制劑的使用與人類疱疹病毒第8型 (Human Herpesvirus-8, HHV-8) 相關。 HHV-8是一種致癌的疱疹病毒與 Kaposi sarcoma 的發生極為相關,案例為一63歲男 性,於2011年進行腎臟移植,術後約11個月,因右腳多處深色紫斑、伴有鱗狀丘疹及 結節來院就診。經由病理切片及病毒檢測後確認為 Kaposi sarcoma,個案接受的治療 包括減量免疫抑制劑及全身性化學治療。移植後的 Kaposi sarcoma 在確診後一般建議 先調整免疫抑制劑的使用,若未改善則可考慮其它療法,但必需注意器官排斥與化學 治療後副作用的風險。 |
英文摘要 | Kaposi sarcoma is a common complication of post-renal transplantation. The relevance of Kaposi sarcoma was associated with immunosuppressants and human herpesvirus-8 (HHV-8). HHV-8 was regarded as an inductive factor of Kaposi sarcoma. In this case, The case was a 63 years old male who performed renal transplant at 2011. After 11 months he came to OPD for the multiple purpura on the right foot with keratotic papules and nodules. He was diagnosed as Kaposi sarcoma after the microscopic examination and viral test and then reduced tacrolimus doses and systemic chemotherapy. It suggested that compromise the dose of immunosuppressive is the first line therapy of post- transplantation Kaposi sarcoma , but maybe induced organ rejection. |
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