頁籤選單縮合
題名 | Successful Unrelated Cord Blood Stem Cell Transplantation in an X-linked Chronic Granulomatous Disease Patient with Disseminated BCG-induced Infection |
---|---|
作者姓名(外文) | Lin, Chao-jen; Wang, Shih-chung; Ku, Cheng-lung; Kao, Jun-kai; Chen, Ming; Liu, Chin-san; | 書刊名 | Pediatrics and Neonatology |
卷期 | 56:5 2015.10[民104.10] |
頁次 | 頁346-350 |
分類號 | 417.5511 |
關鍵詞 | Chronic granulomatous disease; CGD; Disseminated Bacillus Calmette–Guérin (BCG) infection; Umbilical cord blood transplantation; UCBT; |
語文 | 英文(English) |
英文摘要 | A 19-month-old boy with chronic granulomatous disease (CGD) received umbilical cord blood transplantation (UCBT) from an unrelated donor after experiencing a life-threatening disseminated Bacillus Calmette-Guérin infection. After busulfan and cyclophosphamide conditioning, we performed a 5/6-matched UCBT. Engraftment and mixed chimerism was 100% in peripheral blood, and 100% of his neutrophils had normal oxidative burst activity on day 17. The patient is now 3 years old, free from infection, and growing well. To our knowledge, this is the second case of CGD treated with UCBT in Taiwan. His successful outcome illustrates that UCBT in a patient with CGD should be considered early if a human leukocyte antigen-matched donor is not available or the patient has just recovered from a severe infection. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。