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相關文獻
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題名 | Anal Malignant Melanoma=肛門惡性黑色素瘤 |
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作者 | 賴正大; 劉建國; 許自齊; 許希賢; 陳明仁; 梁偉雄; 楊靖國; 洪毓廷; | 書刊名 | 臺灣癌症醫學雜誌 |
卷期 | 28:2 2012.06[民101.06] |
頁次 | 頁86-93 |
分類號 | 416.245 |
關鍵詞 | 惡性黑色素瘤; 肛門直腸黑色素瘤; Malignant melanoma; Anorectal melanoma; |
語文 | 英文(English) |
中文摘要 | 肛門惡性黑色素瘤以少見、癒後不佳著稱,約佔肛門直腸惡性腫瘤的百分之一。黑 色素癌在整個消化道中,好發的位置以肛門最為常見。在全身的黑色素瘤中,肛門直腸 黑色素瘤所佔之比例約為百分之 0.4 至百分之 1.6 之間,位居第三,排名於皮膚及視網膜 之後。過去有關的文獻記載稀少,本病例呈現完整的病史及各種典型的臨床表徵。在治 療方面,因過去均以少數個案病例序列報告為主,對於決定適當的治療方式實屬困難。 外科手術介入的角色迄今沒有定論,所有的手術方式都被認為無法完全根治。因此放射 治療、化學治療、免疫治療、抑或是標靶治療都應考慮加入治療計畫之中,以改善病患 的存活率。 |
英文摘要 | Anal malignant melanoma is notorious for its poor outcomes, accounting for approximately 1% of all anorectal malignancies. In the entire alimentary tract, the disease most frequently originates in the anal canal. Further, as a percentage of all melanomas, 0.4% to 1.6% arise in the anorectal region. Consequently, it is no surprise that, other than the skin and the retina, the anal canal is the most common site of melanoma. Here we presented a case with intact clinical manifestations and comprehensive treatment. Because anal malignant melanoma cases are quite rare, few case series have been reported in the literature, which further compounds the difficulties inherent in treatment of this disease. Additionally, the decision to surgically intervene in cases of malignant melanoma remains controversial, in part because complete remission is hard to achieve with any surgical method. Thus, radiotherapy, chemotherapy, immunotherapy and target therapy should first be considered in the treatment of anorectal melanoma to help improve overall survival rate. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。