查詢結果分析
相關文獻
- Risk Factors and Postoperative Morbidities in Colon Cancer Patients with Preoperative Hypoalbuminemia
- HELLP Syndrome with Antepartum Pulmonary Edema--A Case Report
- Ephedrine-Induced Complete Atrioventricular Block with Ventricular Asystole during Rapid Concomitant Phenytoin Infusion: A Case Report
- Epiglottic Hematoma Secondary to Endotracheal Intubation
- 臺灣地區慢性脊髓損傷病患排尿處置之調查報告
- 小兒使用TPN引起的併發症
- 淺談糖尿病及其併發症
- 慢性阻塞性肺部疾病病患之營養策略
- 難忘的病人--民俗療法之併發症
- Clinical Experience with Ventricular Endomyocardial Biopsy in Chinese Heart Transplant Patients: A Four-Year Survey of 1,208 Consecutive Procedures
頁籤選單縮合
題名 | Risk Factors and Postoperative Morbidities in Colon Cancer Patients with Preoperative Hypoalbuminemia=手術前低血漿白蛋白的結腸癌患者之相關危險因子與併發症分析 |
---|---|
作者 | 謝孟樵; 靳志堅; 黃文詩; 葉重宏; 郭益宏; 陳進勛; 王正儀; Hsieh, Meng-chiao; Chin, Chih-chien; Huang, Wen-shih; Yeh, Chung-hung; Kuo, Yi-hung; Chen, Jinn-shiun; Wang, Jeng-yi; |
期刊 | 中華民國大腸直腸外科醫學會雜誌 |
出版日期 | 20120300 |
卷期 | 23:1 2012.03[民101.03] |
頁次 | 頁6-12 |
分類號 | 416.245 |
語文 | eng |
關鍵詞 | 結腸腫瘤; 低血漿白蛋白; 營養不良; 併發症; Colon cancer; Hypoalbuminemia; Malnutrition; Morbidity; |
中文摘要 | 目的 本研究的目的是藉由病例回溯的方法,鑑別手術前低血漿白蛋白的結腸癌患者之相關危險因子,和手術前低血漿白蛋白症與手術後併發症得關係加以分析探討。 方法 本研究收集自1994 年1 月至2005 年12 月結腸癌接受根治性手術切除的病例,共有2048 例患者。這些患者根據手術前血漿白蛋白濃度被分成兩組,分別為低血漿白蛋白組 (血清白蛋白低於3.5 克/分升) 和正常血漿白蛋白組。 我們分析兩組病人臨床病理上、內科方面相關生理疾病、及手術後併發症上的差異性。 結果 手術前低血漿白蛋白組的病患共395 人 (19.3%);正常血漿白蛋白組的病患共1653人。手術前低血漿白蛋白組與高年紀 (24.8% 比13.1%),右側結腸癌 (48.1% 比36.1%),急診緊急手術 (4.6% 比1.1%),腫瘤分化度較差者 (19.8% 比13.5%),術前高腫瘤胚胎抗原指數 (46.0% 比33.7%),先前的腦血管病變 (5.8% 比3.3%),糖尿病患者 (17.7%比10.7%) 和肝硬化患者 (3.3% 比0.8%) 等等有相關連性。在手術前低血漿白蛋白組中,我們分析出傷口感染,傷口癒合不全 (4.6% 比1.9%),肺炎 (2.3% 比0.1%),膀胱機能障礙 (5.6% 比1.2%),手術吻合處滲漏,或手術吻合處狹窄 (1.8% 比0.7%) 為手術後併發症的獨立危險因子,有達到統計學上的意義 (p < 0.05)。在多重變異分析中,我們也發現手術前低血漿白蛋白為手術後併發症的一個獨立的獨立危險因子。 結論 在結腸癌患者中,有關於手術後併發症而言,手術前低血漿白蛋白是一個獨立的預測因子。 在未來中,更進一步長期研究及長期預後分析研究也是有必要的。 |
英文摘要 | Purpose. The aims of this study were to identify the risk factors associated with preoperative hypoalbuminemia in colon cancer patients and to retrospectively determine the relationship between the preoperative hypoalbuminemia and postoperative morbidities of curative colon surgery. Methods. This study included 2048 consecutive patients who underwent curative surgery for colon cancer between January 1994 and December 2005. These patients were categorized into 2 groups, hypoalbuminemia group (serum albumin level less than 3.5 g/dL) and normal albumin level group. We analyzed clinicopathologic variables, medical illnesses, and postoperative morbidities in these patients. Results. Three hundred and ninety five patients (19.3%) had preoperative hypoalbuminemia and 1653 patients had normal albumin level. Preoperative hypoalbuminemia was associated with old age (24.8% vs. 13.1%), right-sided colon cancer (48.1% vs. 36.1%), emergent operation (4.6% vs.1.1%), poor tumor differentiation (19.8% vs. 13.5%), high preoperative carcinoembryonic antigen levels (46.0% vs. 33.7%), previous cerebrovascular accident (5.8% vs. 3.3%), diabetes mellitus (17.7% vs. 10.7%), and liver cirrhosis (3.3% vs. 0.8%). We identified preoperative hypoalbuminemia as an independent risk factor for postoperative morbidities of wound infection, wound dehiscence (4.6% vs. 1.9%), pneumonia (2.3% vs. 0.1%), bladder dysfunction (5.6% vs. 1.2%), and surgical anastomotic leakage/anastomotic stenosis (1.8% vs. 0.7%). All the abovementioned associations were statistically significant (p < 0.05). Conclusion. Preoperative hypoalbuminemia is an independent predictor of high postoperative morbidity in colon cancer patients. Further longterm follow-up studies are required for analyzing the long-term outcomes of preoperative hypoalbuminemia. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。