頁籤選單縮合
題 名 | Distal Renal Tubular Acidosis in a Patient with Sjögren's Syndrome: Case Report and Literature Review |
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作 者 | Chang, Hwe-lee; Lee, Shinn-shing; Tsai, Shin-hung; | 書刊名 | 臺灣腎臟醫學會雜誌 |
卷 期 | 25:4 2011.12[民100.12] |
頁 次 | 頁201-204 |
分類號 | 415.74 |
關鍵詞 | Renal tubular acidosis; RTA; Hyperchloremic metabolic acidosis; Hypokalemia; Sjögren's syndrome; SS; |
語 文 | 英文(English) |
英文摘要 | Distal renal tubular acidosis (dRTA) is associated with inadequate urinary acidification by the distal nephron. dRTA can present as either an inherited or acquired condition such as autoimmune disorders. The reported prevalence of renal involvement in Sjögren’s syndrome (SS) patients varies widely, ranging from 2 to 67 percent. A defect in distal acidification occurs in up to 25 percent of patients with Sjögren’s syndrome. We report a 32-year-old woman who presented with progressive flaccid quadriparesis. Laboratory investigations showed severe hypokalemia with renal K+ wasting and hyperchloremic metabolic acidosis. A positive urine anion gap with alkaline urine and hypercalciuria with nephrolithiasis were consistent with the diagnosis of distal RTA. Further investigations revealed Sjögren’s syndrome as the underlying cause of distal RTA. |
本系統中英文摘要資訊取自各篇刊載內容。