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題名 | 電氣紡絲製作纖維管狀之結構評估=Evaluation on the Fabrication of Nanofibers Structure by Electrospinning Method |
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作者 | 蔡建皇; Tsai, Chien-huang; |
期刊 | 南開學報 |
出版日期 | 20111200 |
卷期 | 8:2 2011.12[民100.12] |
頁次 | 頁1-5 |
分類號 | 478.1 |
語文 | chi |
關鍵詞 | 電氣紡絲; 纖維管狀結構; 組織工程; Blood vessel engineering; Tissue engineering; Electrospinning; |
中文摘要 | 本研究初步利用電氣紡絲技術將聚乳酸與聚乙二醇進行混合射出,來改良電氣紡絲收集纖維絲的方式,利用不同轉速來調整參數,並在之後持續量測材料表面變化,觀察具方向性排列的纖維管狀結構。在切線速率為0.84 m/s範圍內的纖維,呈現隨機非編織狀,而切線速率為1.86 m/s可呈現編織狀且具方向性增加,當轉速改變,理論上可拉長纖維絲長度,進而控制纖維收集直徑,開發節省材料成本之方案。本案中之纖維絲具親水性的聚乙二醇容易水解,評估大小約為可讓後期繁殖的細胞有足夠的附著空間,有利於細胞的繁殖生長,本案材料有助於生醫敷料的開發而做出貢獻。 |
英文摘要 | This study employed polylactic acid (PLA) and poly(ethylene oxide) (PEO) to fabricate nanofibers by electrospinning, the fibers were typically randomly oriented in the form of nonwoven mats. The structure with disordered fibers was observed in the rotation speed at 0.84 m/s but to form well-ordered nanofibers at 1.86 m/s. In usual, it was believed that the increasing in the rotation speed the longer of nanofibers could be achieved to access. In this case, we produced a nanofibers that was water affinity as well as better biocompatibility for tissue engineering. The tubular structure with aligned topography which mimicked the native artery thus be applied in blood vessel engineering. |
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