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相關文獻
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題名 | Interferon-alpha Therapy Plus Ribavirin Successfully Treat Acute Flare-up of Hepatitis C during Anti-Tuberculous Treatment=成功以干擾素合併Ribavirin治療在一合併肺結核及C型肝炎患者接受抗結核藥物過程中產生之急性肝炎--一病例報告及文獻回顧 |
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作者姓名(中文) | 李孟叡; 王振源; 李麗娜; | 書刊名 | 胸腔醫學 |
卷期 | 26:6 2011.12[民100.12] |
頁次 | 頁352-356 |
分類號 | 418.285 |
關鍵詞 | C型肝炎; 肺結核; 干擾素; Hepatitis C; Tuberculosis; Interferon; |
語文 | 英文(English) |
中文摘要 | 對合併有慢性C型肝炎的肺結核病人,處理抗結核藥物治療過程中產生的急性肝炎是個複雜的議題。我們報告一位合併慢性C型肝炎和肺結核的病人在使用抗結核藥物後產生急性肝炎,我們在嘗試逐一重新加入抗結核藥物卻失敗之後,成功地以干擾素合併ribavirin治療C型肝炎,使肝指數降低,進而完成整個抗結核藥物治療過程。 |
英文摘要 | Hepatitis during anti-tuberculous treatment (HATT) is a complex issue for patients with chronic viral hepatitis C, especially when it recurs after re-challenging the anti-tuberculous drugs. Concerns exist about the safety profile and efficacy of interferon-alpha therapy for active hepatitis C in patients with pulmonary tuberculosis. Herein, we report a 43-year-old man who developed an acute flare-up of hepatitis C during anti-tuberculous treatment and was successfully treated with interferon-alpha and ribavirin. The reduction of liver enzymes correlated well with the hepatitis C viral load, thus enabling the re-challenge with isoniazid and rifampin. This case demonstrates the benefit of interferon-alpha therapy in managing an acute flare-up of hepatitis C during anti-tuberculous treatment. |
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