頁籤選單縮合
題 名 | Risk Factors Associated with Sphingomonas paucimobilis Infection |
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作 者 | Toh, Han-siong; Tay, Hung-tze; Kuar, Wei-khie; Weng, Tzu-chieh; Tang, Hung-jen; Tan, Che-kim; | 書刊名 | Journal of Microbiology, Immunology and Infection |
卷 期 | 44:4 2011.08[民100.08] |
頁 次 | 頁289-295 |
分類號 | 415.15 |
關鍵詞 | Bacteremia; Community-acquired infection; Sphingomonas paucimobilis; |
語 文 | 英文(English) |
英文摘要 | Background: Sphingomonas paucimobilis is rarely isolated from clinical specimens and it is associated with a great variety of infections. The aim of this study is to investigate the microbiological and clinical features of S paucimobilis infection in southern Taiwan. Methods: S paucimobilis isolates from the microbiology laboratory of Chi-Mei Medical Center and their relevant clinical data from October 2005 to October 2009 were retrospectively reviewed. Results: A total of 55 patients with documented S paucimobilis infections were identified. Among them, 29 (52.7%) have community-acquired infections and 13 of them presented with primary bacteremia (44.8%). Multivariate logistic regression showed that community-acquired infection [adjusted odds ratio 13.473, 95% confidence interval (CI) 1.79e101.41, pZ0.01], diabetes mellitus (adjusted odds ratio 7.03, 95% CI 1.16e42.66, pZ0.03), and alcoholism (adjusted OR 10.87, 95% CI 1.00e117.69, pZ0.05) were significant risk factors for S paucimobilis primary bacteremia. Most of those who have health care-associated S paucimobilis infections presented with pneumonia (10 of 26, 38.5%) and only 7.7% presented with catheter-related infection. The overall mortality rate was 5.5%. Conclusion: Community-acquired S paucimobilis infections were not uncommon, mainly presenting with primary bacteremia. Multivariate analysis showed that community-acquired infection, diabetes mellitus, and alcoholism were significant risk factors for primary bacteremia. |
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