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題名 | Retinal Pigment Epithelial Tear after Intravitreous Triamcinolone Acetonide Injection for Fibrovascular Pigment Epithelial Detachment=纖維血管性色素上皮細胞剝離病患之玻璃體內注射丙酮特安皮質醇發生視網膜色素上皮細胞撕裂 |
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作者 | 吳佩昌; 陳勇仁; 郭錫恭; | 書刊名 | 長庚醫誌 |
卷期 | 34:3 2011.05-06[民100.05-06] |
頁次 | 頁320-325 |
分類號 | 416.746 |
關鍵詞 | 新生血管; 丙酮特安皮質醇; 老年性黃斑病變; 視網膜色素上皮細胞; 玻璃體內注射; Neovascularization; Triamcinolone acetonide; Age-related macular degeneration; Retinal pigment epithelial tear; Intravitreous injection; |
語文 | 英文(English) |
英文摘要 | A 78-year-old woman was diagnosed with fibrovascular pigment epithelial detachment (PED) associated with age-related macular degeneration (AMD) affecting both eyes. Due to decreased vision in her left eye (20/2000) and disease progression, the patient received 4 mg of triamcinolone acetonide (TA) by intravitreal injection into her left eye. There were no immediate post-injection complications in the left eye. However, one week later, a retinal pigment epithelial (RPE) tear, temporal-inferior to the fovea in the left eye, was noted and confirmed by fundus photography, fluorescein angiography and optical coherence tomography. In contrast, there no similar RPE tear occurred in her right eye after treated several times by intravitreous bevacizumab injection. Not only anti-vascular endothelium growth factor agents, but also intravitreal TA when used to treat AMD with PED, would seem to induce a RPE tear in the absence of previous or concurrent adjuvant therapy. Further investigations are required to confirm the mechanism by which the RPE tear occurs. |
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