頁籤選單縮合
題 名 | The Correlation among the Percentage of Positive Biopsy Cores from the Dominant Side of Prostate, Adverse Pathology, and Biochemical Failure after Radical Prostatectomy |
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作 者 | Ali Memis; Ozgur Ugurlu; Cuneyt Ozden; Cetin Volkan Oztekin; Binhan Kagan Aktas; Alp Ozgur Akdemir; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷 期 | 27:8 2011.08[民100.08] |
頁 次 | 頁307-313 |
分類號 | 415.863 |
關鍵詞 | Biopsy; Cancer; Prostate; Retropubic prostatectomy; |
語 文 | 英文(English) |
英文摘要 | The aim of this study was to evaluate the correlation among various preoperative clinical variables, including certain prostate needle biopsy parameters, biochemical failure, and adverse pathology, after radical retropubic prostatectomy (RRP). We retrospectively evaluated the records of our 156 patients who underwent RRP because of localized prostate cancer. Serum prostate-specific antigen level, clinical stage, and the information obtained from biopsy [Gleason score, number of positive cores, percentage of positive cores (PPCs) from the dominant side of prostate, and overall PPC] were evaluated as predictors of adverse pathology and biochemical failure. Of the patients, 30.2% (n=38) had nonorgan-confined disease, 19.1% (n=24) had positive surgical margins, 11.9% (n=15) had positive seminal vesicle invasion, and 16.7% (n=21) had biochemical failure after RRP. Multivariate analysis demonstrated that a PPC value of 55% or more from the dominant side of prostate is the only independent predictor of nonorgan-confined disease and seminal vesicle invasion. Clinical stage (T2b), biopsy Gleason score, and PPC values of 55% or more from the dominant side of prostate were found to be statistically significant predictors of positive surgical margin and biochemical failure. Our results support that PPC from the dominant side of prostate is a useful parameter for the prediction of adverse pathology and biochemical failure after RRP. |
本系統中英文摘要資訊取自各篇刊載內容。