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題名 | 奈米化黑豆對雄性老化促進小鼠精子品質之影響=Effects of Nanonized Black Soybean on the Sperm Quality of Mice with Accelerated Male Senescence |
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作者姓名(中文) | 廖俊旺; 王銘富; 梁碧純; 林郁喬; 詹吟菁; | 書刊名 | 臺灣營養學會雜誌 |
卷期 | 36:1 2011.03[民100.03] |
頁次 | 頁1-8 |
分類號 | 411.38 |
關鍵詞 | 奈米; 黑豆; 老化促進小鼠; 精子活動力; 精子濃度; Nano; Black soybean; Senescence-accelerated mice; Sperm motility; Sperm concentration; |
語文 | 中文(Chinese) |
中文摘要 | 黑豆富含抗氧化物質, 包括異黃帥類(isoflavone ) 、皂素( saponin)、花青素( anthocyanin)、維生素E 等, 可能具有抗氧化之功效, 而能降低活性氧物質對生物體的傷害。經奈米化處理所得之黑豆粉末,是否會增強生理效用則尚待討論。因此本研究目的在探討奈米化的黑豆對雄性老化促進小鼠精子品質之影響。實驗以6月齡雄性老化促進小鼠(senescence-accelerated mice;SAMP8 )為對象,將其分為對照組、奈米黑豆組及微米黑豆組,餵食12週;另以正常老化小島(SAMRl) 為正對照組。實驗期間記錯其體重、攝食量, 動物犧牲後稱其罣丸及副罣重量並觀察精子活動力、濃度及副罣組織病理切片變化。結果顯示在軍丸及副罩之相對重量於四組間並無顯著差異( p > O . 0 5 ) 。添加奈米黑豆可提升SA M月精子之活動力及濃度( p < O . 0 5 ) , 而微米黑豆組與對照組相比則無顯著差異( p > O . 05 ) 。副罣組織切片評估結果顯示,奈米及微米黑豆組均較SAM P 8 組有較低的平均精蟲死亡數。綜合以上結果顯示, 黑豆經奈米化處理後, 可增進小鼠精子品質,且效果優於未奈米化黑豆。 |
英文摘要 | Glycine max (L.) Merr. its' may lessen the damage of reaction oxygen species (ROS) due to the antioxidant activities of its isoflavone, saponin, anthocyanin, and vitamin E components. However, the effects of nanonized black soybean on enhancing the physiological function are still unclear. Thus, the objective of this study was to investigate the effects of nanonized black soybean on the spermatozoa quality in senescence-accelerated mice prone-B (SAMP8). Six-month-old male SAMP8 mice were divided into a control group and two experimental groups supplemented with nanonized or micronized bleck soybean for 12 weeks, while senescence-accelerated-resistant mice (SAMR1) were used as the normal control group. The body weight and food intake were recorded during the experimental period. The testis and epididymal weights, motility and concentration of spermatozoa, and the histopathology of the cauda epididymis were also evaluated after sacrifice. Results showed that the relative weights of the testes and epididymis did not differ among the four groups (p>0.05). The nenonized black soybean diet group had significantly better spermatozoa motility and a higher concentration than the SAM P8 control group, whereas the micronized black soybean group did not differ from the control group (p<0.05). Both the nanonized and micronized black soybean diet groups had lower numbers of dead spermatids in the cauda epididymis than the control group. In summary, we concluded that supplementation with nanonized black soybean might promote the sperm quality of mice. Moreover, the effects were better than for the micronized black soybean group. |
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