頁籤選單縮合
題 名 | Patent Ductus Arteriosus Might be a Contributing Factor Affecting on Length of ICU Stay of VLBW Neonates |
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作 者 | 李榮明; 吳秋瑩; 江吉文; 李炳鈺; | 書刊名 | 藥學雜誌 |
卷 期 | 26:4=105 2010.12[民99.12] |
頁 次 | 頁3-8 |
分類號 | 417.5171 |
關鍵詞 | PDA; VLBW neonate; ICU stay; |
語 文 | 英文(English) |
中文摘要 | 延長住院對非常低出生體重( VLBW)新生兒不僅是增加醫療費用且影響其身體健康,本研究之目的是要瞭解延長這些新生兒住加護病房( NICU)的危險因子及分析其結果。從2009年1月1日至 2010年4月30日,總共連續 71個VLBW華人新生兒 (體重 <1500克)曾住在我們的 NICU且進入此研究。這些新生兒體重 605-1495克( 1160.4±244.7克),母親懷孕週數 23 to 35週( 29.30±2.87週)。 VLBW新生兒住 ICU的天數與其體重呈有意義相關, p=0.01( pearson correlation),此意含 VLBW新生兒住 ICU的天數隨著出生體重下降而增加。而與靜脈營養(PN)使用及 beractant使用的統計結果分別是p=0.109(t-test)及 0.129(t-test),無顯著的相關,意含不論是嚴重到需使用 PN之營養不良症或嚴重到需使用 beractant來治療之呼吸窘迫症,對於其住 ICU天數均無明顯的影響。然而,肺支氣管發育不良是 VLBW新生兒住 ICU天數延長之主因,而此症主要是由出生時有呼吸窘迫症及開放性動脈導管所致。有意義的開放性動脈導管可能是 VLBW新生兒住 ICU天數延長之主因;外國人新生兒由於缺乏資料,還需再進一步研究。 |
英文摘要 | Background: The aim of this study was to identify risk factors for lengthened ICU stay of VLBW (very low birth weight) neonates and analyze results as delayed discharge is a big problem for those neonates, not only for medical costs but also for their health. Methods: In total 71 consecutive VLBW ethnic Chinese neonates (body weight <1500 g) admitted to our neonatal intensive care unit (NICU) from Jan. 1, 2009 through Apr. 30, 2010 have entered this study. Their birth weights range from 605 to 1495 g (1160.4±244.7 g), gestational ages from 23 to 35 weeks (29.30±2.87weeks). Results: Significant differences were observed between length of ICU stay of VLBW neonates and their birth weights, p=0.01 (pearson correlation), suggesting that length of VLBW neonatal ICU stay increases with decreased birth weight. No significant differences were observed between ICU stays of VLBW neonates and PN (parenteral nutrition) use or beractant use, p=0.109 (t-test) and 0.129 (t-test), respectively, suggesting that neither malnutrition requiring PN use nor RDS requiring beractant use has an influential effect on length of ICU stay, yet bronchopulmonary dysplasia is a major cause of increased length of hospitalization among VLBW neonates which is mainly caused by RDS (respiratory distress syndrome) or PDA (patent ductus arteriosus). Conclusion: Significant PDA might be a contributing factor affecting on the length of ICU stay of VLBW neonates. Further studies are needed in non-Chinese neonates due to lack of racial varieties in this research. |
本系統中英文摘要資訊取自各篇刊載內容。