頁籤選單縮合
題 名 | Epidemiology and Clinical Peculiarities of Norovirus and Rotavirus Infection in Hospitalized Young Children with Acute Diarrhea in Taiwan, 2009 |
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作 者 | Yang, Shu-yan; Hwang, Kao-pin; Wu, Fang-tzy; Wu, Ho-sheng; Hsiung, Chao Agnes; Chang, Wan-chi; Lin, Jen-shiou; Yang, Shun-cheng; Huang, Sun-lin; Huang, Yhu-chering; | 書刊名 | Journal of Microbiology, Immunology and Infection |
卷 期 | 43:6 2010.12[民99.12] |
頁 次 | 頁506-514 |
分類號 | 417.5472 |
關鍵詞 | Acute diarrhea; Norovirus; Rotavirus; Taiwan; Young children; |
語 文 | 英文(English) |
英文摘要 | BACKGROUND/PURPOSE: Acute diarrhea is one of the most common morbidities in pediatrics worldwide. We conducted a study to investigate the incidence of norovirus in young children hospitalized with acute diarrhea in Taiwan and its clinical peculiarity compared with rotavirus gastroenteritis. METHODS: Between January and December, 2009, patients younger than 5 years and admitted to hospital with acute diarrhea were randomly selected; and their stool samples were collected and tested for presence of rotavirus and norovirus by enzyme immunoassay and reverse transcription-polymerase chain reaction, respectively. The clinical manifestations and laboratory findings of the enrolled patients were analyzed. RESULTS: A total of 989 cases were enrolled with a mean age of 21.6 ± 13.7 months and a male proportion of 56.0%. Rotavirus and norovirus was detected in 20.2% and 14.6% of all patients, respectively. Genogroup II was the predominant strain of norovirus (80.6%). Children aged 6–36 months accounted for the majority of patients positive for rotavirus and norovirus (73.0% and 81.3%, respectively). The incidences of norovirus and rotavirus infection were higher during winter and early spring. Most patients with rotavirus and norovirus diarrhea experienced vomiting (74.9% vs.74.8%, respectively) and fever (94.7% vs. 71.3%, respectively). CONCLUSION: Most young diarrheal patients presenting with vomiting were likely to have norovirus or rotavirus infection. Patients with norovirus diarrhea experienced an absence of, or low-grade fever and longer duration of vomiting compared with those positive for rotavirus infection. A family history of current gastroenteritis may suggest the possibility of norovirus infection. |
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